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• W2184119343 abstract "The aim of the study was initiated to investigate the prevalence of microalbuminuria and its relationship with several clinical and biochemical variables in a population of patients with mild or moderate essential hypertension at patients with or without type 2 diabetes. The study population consisted of 85 patients with hypertension without DM (group A) 162 patients with type 2 DM without or with high blood pressure (group B and C) and 50 control subjects (control group). The patients in groups A, B and C were admitted in hospitals consecutively for one month. For every patient we determined clinical and biochemical variables, plasma insulinemia, HOMA-IR and renal function (albumin to creatinine ratio and GFR). We found the highest prevalence of microalbuminuria (29 %) in the group C (DM with high blood pressure). In groups B (DM without high BP) and A (hypertension without DM) the prevalence of microalbuminuria was 20% and respectively 15% respectively. Moreover, in group A there was a strong positive correlation with diastolic BP (r=0.696; p<0.001) and negative correlation with cholesterol HDL(r=-0.366; p<0.05). Albumin excretion rate was increased in all groups with high risk for vascular damage. The decreasing order of the frequency of renal dysfunction was: group C, group B and group A. These data show that the most important factor of increased AER is related to the presence of diabetes and high blood pressure. This shows that an increased albumin excretion rate could be a valuable marker of vascular damage." @default.
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• W2184119343 date "2011-01-01" @default.
• W2184119343 modified "2023-09-23" @default.
• W2184119343 title "MICROALBUMINURIA IN ESSENTIAL HYPERTENSION AT PATIENTS WITH OR WITHOUT TYPE 2 DIABETES" @default.
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