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- W2332635598 abstract "Purpose: To evaluate the clinical effects of laser trabeculoplasty using a novel 790 nm wavelength titanium-sapphire laser (TLT) compared with a 532 nm Q-switched Nd:YAG laser used in standard selective laser trabeculoplasty (SLT). Methods: Single institution prospective clinical trial of open-angle glaucoma patients randomized to TLT or SLT at the Yale Eye Center from 2011 to 2012. Patients with previous glaucoma surgery or trabeculoplasty were excluded. Trabeculoplasty was performed by a single surgeon unmasked to treatment group. All patients received 360 degrees of treatment. The main outcome measure was intraocular pressure (IOP) at 2 years. Results: Thirty-seven patients were enrolled. The mean baseline IOPs were 19.7 in TLT (n=18) and 20.4 mm Hg in SLT (n=19, P =0.69). At 2 years, the mean IOP was 12.9 mm Hg (35% decrease, P <0.001) in the TLT group and 15.4 mm Hg (25% decrease, P =0.006) in the SLT group. The 2 groups did not differ in glaucoma medication use. Success, defined as IOP<21 mm Hg with >20% reduction from baseline without the need for secondary glaucoma procedures, occurred in 44% of TLT patients and 61% of SLT patients at 1 year and in 22% of TLT patients and 46% of SLT patients at 2 years ( P =0.11). No patients experienced significant pain, anterior chamber reaction, corneal edema, or loss of vision. Conclusions: TLT may be a safe and effective alternative to SLT to lower IOP in patients with open-angle glaucoma." @default.
- W2332635598 created "2016-06-24" @default.
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- W2332635598 date "2016-07-01" @default.
- W2332635598 modified "2023-10-02" @default.
- W2332635598 title "Randomized Controlled Comparison of Titanium-Sapphire Versus Standard Q-Switched Nd:YAG Laser Trabeculoplasty" @default.
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- W2332635598 doi "https://doi.org/10.1097/ijg.0000000000000317" @default.
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