Matches in SemOpenAlex for { <https://semopenalex.org/work/W106986633> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W106986633 endingPage "330" @default.
- W106986633 startingPage "326" @default.
- W106986633 abstract "ABSTRACT Purpose: To assess regression of visual acuity in children who previously participated in three longitudinal studies of therapy with levodopa-carbidopa (L-dopa) plus occlusion for amblyopia. Subjects and Methods: Thirty (91%) of 33 subjects contacted who participated in three similar 7-week, longitudinal dosing studies returned for follow-up. The three previous studies were undertaken approximately 27 (study 1 ), 2 1 (study 2), and 9 (study 3) months prior to this follow-up test session. All subjects received L-dopa for 7 weeks combined with part-time occlusion of the dominant eye after the termination of standard, occlusion only, therapy. Some subjects in study 2 received L-dopa without occlusion. Sixteen subjects with amblyopia who received occlusion only served as a control group. Results: Subjects who received L-dopa plus occlusion demonstrated significant, but similar, amounts of regression of visual acuity from the end of their respective Ldopa studies to the follow-up test session. Subjects in study 1 regressed 1.3 lines, subjects in study 2 regressed 1.5 lines, and subjects in study 3 regressed 1.4 lines. The control group regressed, on average, 1 .1 lines. This was similar to the overall regression found in the groups receiving L-dopa plus occlusion. Subjects in study 2 who received L-dopa without occlusion regressed 2.1 lines, significantly more than the occlusion only group or the L-dopa plus occlusion group. Conclusions: Children with amblyopia show similar amounts of regression of visual acuity after therapy with L-dopa plus occlusion and after therapy with occlusion only. Given that therapy with L-dopa plus occlusion initially improved visual acuity by approximately 1.7 lines following the termination of standard therapy, L-dopa plus occlusion may reset baseline visual acuity and lead to long-term improvement in visual acuity after recidivism." @default.
- W106986633 created "2016-06-24" @default.
- W106986633 creator A5000006296 @default.
- W106986633 creator A5020343019 @default.
- W106986633 creator A5065707075 @default.
- W106986633 creator A5091118895 @default.
- W106986633 date "2002-11-01" @default.
- W106986633 modified "2023-10-01" @default.
- W106986633 title "Long-Term Follow-Up of L-dopa Treatment in Children With Amblyopia" @default.
- W106986633 cites W150326656 @default.
- W106986633 cites W2017120165 @default.
- W106986633 cites W2063817246 @default.
- W106986633 cites W2204047724 @default.
- W106986633 cites W2249908155 @default.
- W106986633 cites W2282937804 @default.
- W106986633 cites W2309664661 @default.
- W106986633 cites W4205129479 @default.
- W106986633 doi "https://doi.org/10.3928/0191-3913-20021101-05" @default.
- W106986633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12458842" @default.
- W106986633 hasPublicationYear "2002" @default.
- W106986633 type Work @default.
- W106986633 sameAs 106986633 @default.
- W106986633 citedByCount "56" @default.
- W106986633 countsByYear W1069866332012 @default.
- W106986633 countsByYear W1069866332013 @default.
- W106986633 countsByYear W1069866332014 @default.
- W106986633 countsByYear W1069866332015 @default.
- W106986633 countsByYear W1069866332016 @default.
- W106986633 countsByYear W1069866332017 @default.
- W106986633 countsByYear W1069866332019 @default.
- W106986633 countsByYear W1069866332020 @default.
- W106986633 countsByYear W1069866332021 @default.
- W106986633 countsByYear W1069866332022 @default.
- W106986633 countsByYear W1069866332023 @default.
- W106986633 crossrefType "journal-article" @default.
- W106986633 hasAuthorship W106986633A5000006296 @default.
- W106986633 hasAuthorship W106986633A5020343019 @default.
- W106986633 hasAuthorship W106986633A5065707075 @default.
- W106986633 hasAuthorship W106986633A5091118895 @default.
- W106986633 hasConcept C118487528 @default.
- W106986633 hasConcept C126322002 @default.
- W106986633 hasConcept C2776268601 @default.
- W106986633 hasConcept C2778257484 @default.
- W106986633 hasConcept C71924100 @default.
- W106986633 hasConceptScore W106986633C118487528 @default.
- W106986633 hasConceptScore W106986633C126322002 @default.
- W106986633 hasConceptScore W106986633C2776268601 @default.
- W106986633 hasConceptScore W106986633C2778257484 @default.
- W106986633 hasConceptScore W106986633C71924100 @default.
- W106986633 hasIssue "6" @default.
- W106986633 hasLocation W1069866331 @default.
- W106986633 hasLocation W1069866332 @default.
- W106986633 hasOpenAccess W106986633 @default.
- W106986633 hasPrimaryLocation W1069866331 @default.
- W106986633 hasRelatedWork W1160629858 @default.
- W106986633 hasRelatedWork W2077760523 @default.
- W106986633 hasRelatedWork W2104751016 @default.
- W106986633 hasRelatedWork W2349999257 @default.
- W106986633 hasRelatedWork W2354275354 @default.
- W106986633 hasRelatedWork W2362796790 @default.
- W106986633 hasRelatedWork W2387330792 @default.
- W106986633 hasRelatedWork W2416098508 @default.
- W106986633 hasRelatedWork W2960272337 @default.
- W106986633 hasRelatedWork W4243702326 @default.
- W106986633 hasVolume "39" @default.
- W106986633 isParatext "false" @default.
- W106986633 isRetracted "false" @default.
- W106986633 magId "106986633" @default.
- W106986633 workType "article" @default.