FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1166034911> ?p ?o ?g. }

• W1166034911 endingPage "66" @default.
• W1166034911 startingPage "59" @default.
• W1166034911 abstract "This chapter describes existing animal models of colonization and reviews what these various models have taught us about pneumococcal carriage. The most widely studied model of pneumococcal colonization is the mouse model. Infant rat models of pneumococcal colonization have also been described in several studies. A buccal mucosa model was also developed to evaluate the impact of ambient temperatures on pneumococcal colonization. The major limitation of chinchilla model is the relative lack of chinchilla reagents, as well as the expense. Animal models have provided information about the contribution of specific bacterial components to colonization, the first step in the pathogenesis of all pneumococcal disease. Different laboratories have used different mouse strains, which often vary in susceptibility to pneumococcal colonization and disease. Murine models of pneumococcal colonization have helped enhance the understanding of acquired immunity to pneumococcal colonization. The infant rat model of intralitter spread was used to evaluate the impact of systemic anticapsular antibodies in the prevention of pneumococcal colonization. The administration of bacterial polysaccharide immune globulin (from hyperimmune sera obtained from adults immunized with pneumococcal, Haemophilus influenzae type b, and meningococcal pure-polysaccharide vaccines) to infant rats reduced the likelihood of pneumococcal colonization by about 50%. The development of purified-protein vaccines or whole-cell vaccines, however, faces several challenges, including the inherent difficulty of studying colonization in animals that normally do not carry Streptococcus pneumoniae in their respiratory trees." @default.
• W1166034911 created "2016-06-24" @default.
• W1166034911 creator A5066405485 @default.
• W1166034911 creator A5072804304 @default.
• W1166034911 date "2014-04-30" @default.
• W1166034911 modified "2023-09-27" @default.
• W1166034911 title "Animal Models of Pneumococcal Colonization" @default.
• W1166034911 cites W1508637059 @default.
• W1166034911 cites W1803983316 @default.
• W1166034911 cites W1925514709 @default.
• W1166034911 cites W1976115338 @default.
• W1166034911 cites W1978465166 @default.
• W1166034911 cites W1983401418 @default.
• W1166034911 cites W2011696576 @default.
• W1166034911 cites W2014054856 @default.
• W1166034911 cites W2022243863 @default.
• W1166034911 cites W2047047908 @default.
• W1166034911 cites W2055892940 @default.
• W1166034911 cites W2058525652 @default.
• W1166034911 cites W2070088956 @default.
• W1166034911 cites W2071731441 @default.
• W1166034911 cites W2071916306 @default.
• W1166034911 cites W2087453197 @default.
• W1166034911 cites W2097750123 @default.
• W1166034911 cites W2098483219 @default.
• W1166034911 cites W2100680575 @default.
• W1166034911 cites W2103637444 @default.
• W1166034911 cites W2105584669 @default.
• W1166034911 cites W2105668129 @default.
• W1166034911 cites W2118244289 @default.
• W1166034911 cites W2118878242 @default.
• W1166034911 cites W2119569074 @default.
• W1166034911 cites W2120086913 @default.
• W1166034911 cites W2122873066 @default.
• W1166034911 cites W2127657315 @default.
• W1166034911 cites W2130115123 @default.
• W1166034911 cites W2130198156 @default.
• W1166034911 cites W2133454819 @default.
• W1166034911 cites W2133693845 @default.
• W1166034911 cites W2135195475 @default.
• W1166034911 cites W2138424202 @default.
• W1166034911 cites W2139743462 @default.
• W1166034911 cites W2139857977 @default.
• W1166034911 cites W2142581528 @default.
• W1166034911 cites W2144240057 @default.
• W1166034911 cites W2146786054 @default.
• W1166034911 cites W2146799886 @default.
• W1166034911 cites W2147710174 @default.
• W1166034911 cites W2148143691 @default.
• W1166034911 cites W2150638118 @default.
• W1166034911 cites W2151428889 @default.
• W1166034911 cites W2153114735 @default.
• W1166034911 cites W2153374503 @default.
• W1166034911 cites W2156659808 @default.
• W1166034911 cites W2160515343 @default.
• W1166034911 cites W2161963638 @default.
• W1166034911 cites W2162339585 @default.
• W1166034911 cites W2167840853 @default.
• W1166034911 doi "https://doi.org/10.1128/9781555815820.ch5" @default.
• W1166034911 hasPublicationYear "2014" @default.
• W1166034911 type Work @default.
• W1166034911 sameAs 1166034911 @default.
• W1166034911 citedByCount "3" @default.
• W1166034911 countsByYear W11660349112012 @default.
• W1166034911 countsByYear W11660349112017 @default.
• W1166034911 countsByYear W11660349112019 @default.
• W1166034911 crossrefType "book-chapter" @default.
• W1166034911 hasAuthorship W1166034911A5066405485 @default.
• W1166034911 hasAuthorship W1166034911A5072804304 @default.
• W1166034911 hasConcept C203014093 @default.
• W1166034911 hasConcept C2776152631 @default.
• W1166034911 hasConcept C2776925733 @default.
• W1166034911 hasConcept C2776927270 @default.
• W1166034911 hasConcept C2781253189 @default.
• W1166034911 hasConcept C501593827 @default.
• W1166034911 hasConcept C86803240 @default.
• W1166034911 hasConcept C8891405 @default.
• W1166034911 hasConcept C89423630 @default.
• W1166034911 hasConceptScore W1166034911C203014093 @default.
• W1166034911 hasConceptScore W1166034911C2776152631 @default.
• W1166034911 hasConceptScore W1166034911C2776925733 @default.
• W1166034911 hasConceptScore W1166034911C2776927270 @default.
• W1166034911 hasConceptScore W1166034911C2781253189 @default.
• W1166034911 hasConceptScore W1166034911C501593827 @default.
• W1166034911 hasConceptScore W1166034911C86803240 @default.
• W1166034911 hasConceptScore W1166034911C8891405 @default.
• W1166034911 hasConceptScore W1166034911C89423630 @default.
• W1166034911 hasLocation W11660349111 @default.
• W1166034911 hasOpenAccess W1166034911 @default.
• W1166034911 hasPrimaryLocation W11660349111 @default.
• W1166034911 hasRelatedWork W1978333007 @default.
• W1166034911 hasRelatedWork W1996089200 @default.
• W1166034911 hasRelatedWork W2026514246 @default.
• W1166034911 hasRelatedWork W2036082547 @default.
• W1166034911 hasRelatedWork W2056400335 @default.
• W1166034911 hasRelatedWork W2057024771 @default.
• W1166034911 hasRelatedWork W2105117123 @default.
• W1166034911 hasRelatedWork W2109283478 @default.

• next