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• W1455560909 abstract "This chapter describes recent advances in understanding the molecules—individually and in complexes—that are controlling the events of the cell cycle in model systems, such as yeast and early amphibian, and in transformed cell types, such as HeLa cells. The chapter presents the events that occur in early murine embryos and explains the ways in which probes derived from other systems have been used successfully to study the molecular mechanisms operating in early mouse development. The chapter also discusses the way the repertoire of techniques advances the understanding of the molecular mechanisms underlying the control of the cell cycle in early mammalian development. Yeasts provide good model systems to study cell-cycle control as they are simple single cell eukaryotes having less complicated cell-cycle regulation. The cell cycles of yeast are not exactly identical to those in higher organisms, such as mammals. As with higher eukaryotes, a spindle forms and chromosomes condense, but unlike higher eukaryotes, there is no breakdown of the nuclear envelope and the cell divides by medial fission." @default.
• W1455560909 created "2016-06-24" @default.
• W1455560909 creator A5065168589 @default.
• W1455560909 date "1991-01-01" @default.
• W1455560909 modified "2023-09-25" @default.
• W1455560909 title "Molecular Basis of Cell Cycle Control in Early Mouse Embryos" @default.
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• W1455560909 doi "https://doi.org/10.1016/s0074-7696(08)60509-4" @default.
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