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- W1493986842 abstract "Nigeran (mycodextran), an unbranched glucan consisting of alternating α,1–4 and α,1–3 linkages, is accumulated intracellularly by Aspergillus aculeatus , under conditions of nitrogen limitation and low p H (optimum p H 5.0). Both conditions are necessary. Nigeran is synthesized de novo from exogenous glucose and accounts for about 20% of the glucose transported by the mycelium. The polymer is diluted out but not degraded when the mycelium is transferred to fresh medium containing NH 4 + . Cycloheximide prevents development of the nigeran biosynthetic system. The addition of substrate levels of NH 4 + to nigeran-accumulating mycelium immediately suppresses further nigeran buildup, presumably by diverting glucose to the biosynthesis of amino acids, nucleotides, etc." @default.
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- W1493986842 date "1973-02-01" @default.
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- W1493986842 title "Regulation of Nigeran Accumulation by Aspergillus aculeatus" @default.
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- W1493986842 doi "https://doi.org/10.1128/jb.113.2.856-862.1973" @default.
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