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• W1586472992 endingPage "CMC.S355" @default.
• W1586472992 startingPage "CMC.S355" @default.
• W1586472992 abstract "AimTo clarify the significance of heart rate variability for the evaluation of an autonomic nervous system (ANS) in the normal fetus using fetal magnetocardiography (FMCG). MethodsSubjects consisted of normal pregnancy (n = 35) at 28-39 weeks gestation. FMCG was recorded using 64-channel magnetocardiography (MCG) in a magnetically shielded room. The QRS interval was derived from signal-averaged MCG. The R-R interval variability induced by an R-wave trigger was eventually adopted to calculate for time-domain and frequency domain analysis. The power spectrum in the frequency domain was derived from frequency-field components using the maximum entropy method of fetal heart rate variability. Based on frequency analysis, the ranges of the LF and HF domains were defined as 0.01-0.15 and 0.15-0.4 Hz, respectively. We defined a coefficient of variance (CVRR) as an index of parasympathetic activity, and defined a low frequency/high frequency (LF/HF) ratio as a sympathetic activity. ResultsThe value of CVRR in the normal pregnancy group displayed a slight increasing trend with gestational age (y = 1.77 + 0.10x; r = 0.32). In contrast, the LF/HF ratio in the normal pregnancy group clearly increased over the gestational period (one-way ANOVA: P = 0.003). ConclusionsAnalyses based on the time and frequency domains of heart rate variability using FMCG enable an evaluation of fetal ANS activity. Sympathetic nervous activity increased with gestational age in the normal pregnancy group." @default.
• W1586472992 created "2016-06-24" @default.
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• W1586472992 date "2008-01-01" @default.
• W1586472992 modified "2023-09-26" @default.
• W1586472992 title "Assessment of Fetal Autonomic Nervous System Activity by Fetal Magnetocardiography" @default.
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• W1586472992 doi "https://doi.org/10.4137/cmc.s355" @default.
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