Matches in SemOpenAlex for { <https://semopenalex.org/work/W1607177112> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1607177112 endingPage "9789" @default.
- W1607177112 startingPage "9783" @default.
- W1607177112 abstract "The specific mammalian collagenase isolated from cultures of metastatic mouse PMT sarcoma cells cleaves murine procollagen IV into two segments, of approximate mass ratio 3:1. These fragments were separated by velocity sedimentation, visualized by electron microscopy, and analyzed. The longer COOH-terminal procollagen segment has a 270-nm collagenous portion with a knob at one end. This knob consists of the three previously identified, noncollagenous carboxyl propeptides, of approximately 30,000 daltons each. These carboxyl propeptides are chain-specific, and the three chains of each segment have the same amino to carboxyl orientation. The collagenase cuts through all three chains at one site, and the three-component chains of both the longer COOH-terminal procollagen segment and the shorter NH2-terminal procollagen segment are linked by interchain disulfide bridges. The enzyme cuts off the same COOH-terminal procollagen segment from procollagen IV monomers and tetramers, and the flexibility of this segment is similar to that of interstitial helices. The amino ends of the NH2-terminal procollagen segments derived from tetramers remain joined as the 32-nm long 7 S collagen junctional complex, and the remaining 89-nm long projecting threads are significantly more flexible than the COOH-terminal procollagen segment. The electrophoretic mobilities of the enzyme cleavage products are consistent with a heterotrimeric composition of this procollagen IV." @default.
- W1607177112 created "2016-06-24" @default.
- W1607177112 creator A5000224317 @default.
- W1607177112 creator A5020797457 @default.
- W1607177112 creator A5044607051 @default.
- W1607177112 creator A5068133733 @default.
- W1607177112 creator A5086257422 @default.
- W1607177112 date "1984-08-01" @default.
- W1607177112 modified "2023-10-17" @default.
- W1607177112 title "Characterization of the procollagen IV cleavage products produced by a specific tumor collagenase." @default.
- W1607177112 cites W1481936182 @default.
- W1607177112 cites W1491683643 @default.
- W1607177112 cites W1492741817 @default.
- W1607177112 cites W1495765353 @default.
- W1607177112 cites W1536187379 @default.
- W1607177112 cites W1563546913 @default.
- W1607177112 cites W1568187381 @default.
- W1607177112 cites W1928394038 @default.
- W1607177112 cites W1971236245 @default.
- W1607177112 cites W1986937920 @default.
- W1607177112 cites W1995249913 @default.
- W1607177112 cites W1995493762 @default.
- W1607177112 cites W1995797967 @default.
- W1607177112 cites W2014043577 @default.
- W1607177112 cites W2019479885 @default.
- W1607177112 cites W2034244905 @default.
- W1607177112 cites W2034277598 @default.
- W1607177112 cites W2037873455 @default.
- W1607177112 cites W2056876653 @default.
- W1607177112 cites W2057579044 @default.
- W1607177112 cites W2062510144 @default.
- W1607177112 cites W2076300996 @default.
- W1607177112 cites W2100837269 @default.
- W1607177112 cites W2170424061 @default.
- W1607177112 cites W2333443761 @default.
- W1607177112 doi "https://doi.org/10.1016/s0021-9258(17)42768-2" @default.
- W1607177112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6086649" @default.
- W1607177112 hasPublicationYear "1984" @default.
- W1607177112 type Work @default.
- W1607177112 sameAs 1607177112 @default.
- W1607177112 citedByCount "164" @default.
- W1607177112 countsByYear W16071771122014 @default.
- W1607177112 countsByYear W16071771122015 @default.
- W1607177112 countsByYear W16071771122016 @default.
- W1607177112 countsByYear W16071771122018 @default.
- W1607177112 countsByYear W16071771122021 @default.
- W1607177112 countsByYear W16071771122022 @default.
- W1607177112 countsByYear W16071771122023 @default.
- W1607177112 crossrefType "journal-article" @default.
- W1607177112 hasAuthorship W1607177112A5000224317 @default.
- W1607177112 hasAuthorship W1607177112A5020797457 @default.
- W1607177112 hasAuthorship W1607177112A5044607051 @default.
- W1607177112 hasAuthorship W1607177112A5068133733 @default.
- W1607177112 hasAuthorship W1607177112A5086257422 @default.
- W1607177112 hasBestOaLocation W16071771121 @default.
- W1607177112 hasConcept C151730666 @default.
- W1607177112 hasConcept C153911025 @default.
- W1607177112 hasConcept C175156509 @default.
- W1607177112 hasConcept C181199279 @default.
- W1607177112 hasConcept C185592680 @default.
- W1607177112 hasConcept C2778394429 @default.
- W1607177112 hasConcept C43369102 @default.
- W1607177112 hasConcept C55493867 @default.
- W1607177112 hasConcept C64348721 @default.
- W1607177112 hasConcept C86803240 @default.
- W1607177112 hasConceptScore W1607177112C151730666 @default.
- W1607177112 hasConceptScore W1607177112C153911025 @default.
- W1607177112 hasConceptScore W1607177112C175156509 @default.
- W1607177112 hasConceptScore W1607177112C181199279 @default.
- W1607177112 hasConceptScore W1607177112C185592680 @default.
- W1607177112 hasConceptScore W1607177112C2778394429 @default.
- W1607177112 hasConceptScore W1607177112C43369102 @default.
- W1607177112 hasConceptScore W1607177112C55493867 @default.
- W1607177112 hasConceptScore W1607177112C64348721 @default.
- W1607177112 hasConceptScore W1607177112C86803240 @default.
- W1607177112 hasIssue "15" @default.
- W1607177112 hasLocation W16071771121 @default.
- W1607177112 hasOpenAccess W1607177112 @default.
- W1607177112 hasPrimaryLocation W16071771121 @default.
- W1607177112 hasRelatedWork W1588590018 @default.
- W1607177112 hasRelatedWork W2011966791 @default.
- W1607177112 hasRelatedWork W2025268777 @default.
- W1607177112 hasRelatedWork W2037996622 @default.
- W1607177112 hasRelatedWork W2039729904 @default.
- W1607177112 hasRelatedWork W2360210661 @default.
- W1607177112 hasRelatedWork W2949457366 @default.
- W1607177112 hasRelatedWork W2949992629 @default.
- W1607177112 hasRelatedWork W2949998934 @default.
- W1607177112 hasRelatedWork W3043266616 @default.
- W1607177112 hasVolume "259" @default.
- W1607177112 isParatext "false" @default.
- W1607177112 isRetracted "false" @default.
- W1607177112 magId "1607177112" @default.
- W1607177112 workType "article" @default.