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• W1718572743 abstract "Abstract Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural development and function. As key components of brain tissue, omega-3 PUFAs play critical roles in brain development and function, and a lack of these fatty acids has been implicated in a number of mental health conditions over the lifespan, including schizophrenia. We have previously shown that a 12-week intervention with omega-3 PUFAs reduced the risk of progression to psychotic disorder in young people with subthreshold psychotic states for a 12-month period compared with placebo. We have now completed a longer-term follow-up of this randomized, double-blind, placebo-controlled trial, at a median of 6.7 years. Here we show that brief intervention with omega-3 PUFAs reduced both the risk of progression to psychotic disorder and psychiatric morbidity in general in this study. The majority of the individuals from the omega-3 group did not show severe functional impairment and no longer experienced attenuated psychotic symptoms at follow-up." @default.
• W1718572743 created "2016-06-24" @default.
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• W1718572743 date "2015-08-11" @default.
• W1718572743 modified "2023-10-05" @default.
• W1718572743 title "Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study" @default.
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• W1718572743 doi "https://doi.org/10.1038/ncomms8934" @default.
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