Matches in SemOpenAlex for { <https://semopenalex.org/work/W1738005890> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1738005890 endingPage "500" @default.
- W1738005890 startingPage "1495" @default.
- W1738005890 abstract "To compare the efficacy and safety of original (Plavix) and generic (Apolets) clopidogrel 600 mg loading in patients planning to undergo coronary angiography.This is an experimental design, parallel, randomized-controlled study. Coronary artery disease patients planned for cardiac catheterization were recruited Patients were randomized to receive either original or generic clopidogrel 600 mg loading dose. Platelet aggregation induced by 5 micromol/L and 20 micromol/L adenosine diphosphate (ADP) was measured by light transmission aggregometry (LTA) at baseline and 6 hours after clopidogrel 600 mg administration.Forty-nine patients were enrolled, 24 patients received original clopidogrel, and 25 patients received generic clopidogrel. After six hours of loading, there was significantly reduction in platelet aggregation induced by adenosine 5 micromol/L from 41.08 +/- 3.04% to 19.50 +/- 1.68% (p < 0.001) in original group compared to 36.76 +/- 2.66% to 21.32 +/- 2.60% (p < 0.001) in generic group. When induced by 20 micromol/L, the platelet aggregation was reduced from 58.50 +/- 2.09% to 32.25 +/- 2.30% (p < 0.001) in original group and from 61.12 +/- 2.54% to 30.04 +/- 3.14% (p < 0.001) in generic group. There was no significant difference between original and generic clopidogrel in reducing platelet aggregation induced by both adenosine 5 and 20 micromol/L. Groin hematoma was found in one case (4.2%) in the original clopidogrel group.Generic clopidogrel (Apolets) 600 mg loading dose is as effective as original clopidogrel (Plavix) in term of platelet aggregation inhibition." @default.
- W1738005890 created "2016-06-24" @default.
- W1738005890 creator A5005067789 @default.
- W1738005890 creator A5005421031 @default.
- W1738005890 creator A5021114330 @default.
- W1738005890 creator A5050266475 @default.
- W1738005890 creator A5052930746 @default.
- W1738005890 creator A5066150656 @default.
- W1738005890 creator A5069517926 @default.
- W1738005890 creator A5070254342 @default.
- W1738005890 date "2012-12-01" @default.
- W1738005890 modified "2023-09-23" @default.
- W1738005890 title "Comparison of original and generic clopidogrel 600 mg loading dose in the patients who planned undergoing coronary angiography." @default.
- W1738005890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23390778" @default.
- W1738005890 hasPublicationYear "2012" @default.
- W1738005890 type Work @default.
- W1738005890 sameAs 1738005890 @default.
- W1738005890 citedByCount "3" @default.
- W1738005890 countsByYear W17380058902014 @default.
- W1738005890 countsByYear W17380058902015 @default.
- W1738005890 countsByYear W17380058902020 @default.
- W1738005890 crossrefType "journal-article" @default.
- W1738005890 hasAuthorship W1738005890A5005067789 @default.
- W1738005890 hasAuthorship W1738005890A5005421031 @default.
- W1738005890 hasAuthorship W1738005890A5021114330 @default.
- W1738005890 hasAuthorship W1738005890A5050266475 @default.
- W1738005890 hasAuthorship W1738005890A5052930746 @default.
- W1738005890 hasAuthorship W1738005890A5066150656 @default.
- W1738005890 hasAuthorship W1738005890A5069517926 @default.
- W1738005890 hasAuthorship W1738005890A5070254342 @default.
- W1738005890 hasConcept C126322002 @default.
- W1738005890 hasConcept C164705383 @default.
- W1738005890 hasConcept C168563851 @default.
- W1738005890 hasConcept C2777385415 @default.
- W1738005890 hasConcept C2777399203 @default.
- W1738005890 hasConcept C2777849778 @default.
- W1738005890 hasConcept C2778213512 @default.
- W1738005890 hasConcept C2993802102 @default.
- W1738005890 hasConcept C35294091 @default.
- W1738005890 hasConcept C42219234 @default.
- W1738005890 hasConcept C49059817 @default.
- W1738005890 hasConcept C500558357 @default.
- W1738005890 hasConcept C71924100 @default.
- W1738005890 hasConcept C89560881 @default.
- W1738005890 hasConcept C98274493 @default.
- W1738005890 hasConceptScore W1738005890C126322002 @default.
- W1738005890 hasConceptScore W1738005890C164705383 @default.
- W1738005890 hasConceptScore W1738005890C168563851 @default.
- W1738005890 hasConceptScore W1738005890C2777385415 @default.
- W1738005890 hasConceptScore W1738005890C2777399203 @default.
- W1738005890 hasConceptScore W1738005890C2777849778 @default.
- W1738005890 hasConceptScore W1738005890C2778213512 @default.
- W1738005890 hasConceptScore W1738005890C2993802102 @default.
- W1738005890 hasConceptScore W1738005890C35294091 @default.
- W1738005890 hasConceptScore W1738005890C42219234 @default.
- W1738005890 hasConceptScore W1738005890C49059817 @default.
- W1738005890 hasConceptScore W1738005890C500558357 @default.
- W1738005890 hasConceptScore W1738005890C71924100 @default.
- W1738005890 hasConceptScore W1738005890C89560881 @default.
- W1738005890 hasConceptScore W1738005890C98274493 @default.
- W1738005890 hasIssue "12" @default.
- W1738005890 hasLocation W17380058901 @default.
- W1738005890 hasOpenAccess W1738005890 @default.
- W1738005890 hasPrimaryLocation W17380058901 @default.
- W1738005890 hasRelatedWork W1738005890 @default.
- W1738005890 hasRelatedWork W175512219 @default.
- W1738005890 hasRelatedWork W186366351 @default.
- W1738005890 hasRelatedWork W1972045176 @default.
- W1738005890 hasRelatedWork W2009822852 @default.
- W1738005890 hasRelatedWork W2064855259 @default.
- W1738005890 hasRelatedWork W2116611908 @default.
- W1738005890 hasRelatedWork W2739317526 @default.
- W1738005890 hasRelatedWork W3025260826 @default.
- W1738005890 hasRelatedWork W3032583079 @default.
- W1738005890 hasVolume "95" @default.
- W1738005890 isParatext "false" @default.
- W1738005890 isRetracted "false" @default.
- W1738005890 magId "1738005890" @default.
- W1738005890 workType "article" @default.