FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1944231750> ?p ?o ?g. }

• W1944231750 endingPage "9" @default.
• W1944231750 startingPage "950" @default.
• W1944231750 abstract "Many Duchenne muscular dystrophy (DMD) patients are known to have rare staining dystrophin-positive fibers, termed revertants. The precise etiology of these rare fibers is unknown. The most likely explanation, however, is somatic mosaicism or somatic reversion/suppression. Immunocytochemistry was performed on serial sections from deleted and nondeleted patients, with a panel of antibodies--9219, 1377, 9218, and Dys-2--that span dystrophin. Both familial and nonfamilial patients possessed revertants. Either the same clusters or individual revertant fibers stained with amino- and carboxyl-terminal antibodies in all 14 DMD patients. In patients with deletions, revertants did not stain with antibodies raised to polypeptide sequences within the deletion. These results indicate that positively staining fibers are not the result of somatic mosaicism in deleted patients. Five of 10 patients without deletions had revertant fibers. In two of these patients, the revertant fibers did not stain with antibody 9218, which was generated against amino acids 2305-2554 and which corresponds to exons 48-52. The remaining antibodies from the panel stained the same fibers on separate serial sections in these two patients. The most likely mechanism giving rise to these positively staining fibers is a second site in-frame deletion. Antibodies generated to polypeptide sequences within deletions can be used to control for the natural occurrence of revertant fibers in myoblast transfer studies and may be useful in the detection of point mutations." @default.
• W1944231750 created "2016-06-24" @default.
• W1944231750 creator A5039450712 @default.
• W1944231750 creator A5047809221 @default.
• W1944231750 creator A5056775376 @default.
• W1944231750 creator A5077668464 @default.
• W1944231750 creator A5087026335 @default.
• W1944231750 creator A5087777841 @default.
• W1944231750 date "1992-05-01" @default.
• W1944231750 modified "2023-09-29" @default.
• W1944231750 title "Somatic reversion/suppression in Duchenne muscular dystrophy (DMD): evidence supporting a frame-restoring mechanism in rare dystrophin-positive fibers." @default.
• W1944231750 cites W1550640228 @default.
• W1944231750 cites W1628366259 @default.
• W1944231750 cites W1800368693 @default.
• W1944231750 cites W1970561503 @default.
• W1944231750 cites W1986088843 @default.
• W1944231750 cites W1986576629 @default.
• W1944231750 cites W1990335000 @default.
• W1944231750 cites W1991027600 @default.
• W1944231750 cites W1998615097 @default.
• W1944231750 cites W2015631186 @default.
• W1944231750 cites W2018600945 @default.
• W1944231750 cites W2027436201 @default.
• W1944231750 cites W2034309480 @default.
• W1944231750 cites W2036426068 @default.
• W1944231750 cites W2038685361 @default.
• W1944231750 cites W2043391835 @default.
• W1944231750 cites W2044530341 @default.
• W1944231750 cites W2046966094 @default.
• W1944231750 cites W2059658715 @default.
• W1944231750 cites W2060063694 @default.
• W1944231750 cites W2063938246 @default.
• W1944231750 cites W2064788529 @default.
• W1944231750 cites W2066180106 @default.
• W1944231750 cites W2068599642 @default.
• W1944231750 cites W2070732085 @default.
• W1944231750 cites W2070936696 @default.
• W1944231750 cites W2072832813 @default.
• W1944231750 cites W2132205230 @default.
• W1944231750 cites W2161930071 @default.
• W1944231750 cites W2167021585 @default.
• W1944231750 cites W230396661 @default.
• W1944231750 cites W281458651 @default.
• W1944231750 cites W4233309275 @default.
• W1944231750 cites W89647785 @default.
• W1944231750 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1682584" @default.
• W1944231750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1570844" @default.
• W1944231750 hasPublicationYear "1992" @default.
• W1944231750 type Work @default.
• W1944231750 sameAs 1944231750 @default.
• W1944231750 citedByCount "64" @default.
• W1944231750 countsByYear W19442317502012 @default.
• W1944231750 countsByYear W19442317502013 @default.
• W1944231750 countsByYear W19442317502014 @default.
• W1944231750 countsByYear W19442317502015 @default.
• W1944231750 countsByYear W19442317502016 @default.
• W1944231750 countsByYear W19442317502017 @default.
• W1944231750 countsByYear W19442317502018 @default.
• W1944231750 countsByYear W19442317502019 @default.
• W1944231750 countsByYear W19442317502020 @default.
• W1944231750 countsByYear W19442317502022 @default.
• W1944231750 countsByYear W19442317502023 @default.
• W1944231750 crossrefType "journal-article" @default.
• W1944231750 hasAuthorship W1944231750A5039450712 @default.
• W1944231750 hasAuthorship W1944231750A5047809221 @default.
• W1944231750 hasAuthorship W1944231750A5056775376 @default.
• W1944231750 hasAuthorship W1944231750A5077668464 @default.
• W1944231750 hasAuthorship W1944231750A5087026335 @default.
• W1944231750 hasAuthorship W1944231750A5087777841 @default.
• W1944231750 hasConcept C104317684 @default.
• W1944231750 hasConcept C127716648 @default.
• W1944231750 hasConcept C134018914 @default.
• W1944231750 hasConcept C134305767 @default.
• W1944231750 hasConcept C142724271 @default.
• W1944231750 hasConcept C153911025 @default.
• W1944231750 hasConcept C159654299 @default.
• W1944231750 hasConcept C2778943923 @default.
• W1944231750 hasConcept C2779030066 @default.
• W1944231750 hasConcept C2780394045 @default.
• W1944231750 hasConcept C2781294515 @default.
• W1944231750 hasConcept C35866371 @default.
• W1944231750 hasConcept C36823959 @default.
• W1944231750 hasConcept C54355233 @default.
• W1944231750 hasConcept C70883133 @default.
• W1944231750 hasConcept C71924100 @default.
• W1944231750 hasConcept C74864618 @default.
• W1944231750 hasConcept C86803240 @default.
• W1944231750 hasConceptScore W1944231750C104317684 @default.
• W1944231750 hasConceptScore W1944231750C127716648 @default.
• W1944231750 hasConceptScore W1944231750C134018914 @default.
• W1944231750 hasConceptScore W1944231750C134305767 @default.
• W1944231750 hasConceptScore W1944231750C142724271 @default.
• W1944231750 hasConceptScore W1944231750C153911025 @default.
• W1944231750 hasConceptScore W1944231750C159654299 @default.
• W1944231750 hasConceptScore W1944231750C2778943923 @default.
• W1944231750 hasConceptScore W1944231750C2779030066 @default.
• W1944231750 hasConceptScore W1944231750C2780394045 @default.
• W1944231750 hasConceptScore W1944231750C2781294515 @default.

• next