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- W1967090815 abstract "The assessment of oocyte quality in human in vitro fertilization (IVF) is getting increasing attention from embryologists. Oocyte selection and the identification of the best oocytes, in fact, would help to limit embryo overproduction and to improve the results of oocyte cryostorage programs. Follicular fluid (FF) is easily available during oocyte pick-up and theorically represents an optimal source on non-invasive biochemical predictors of oocyte quality. Unfortunately, however, the studies aiming to find a good molecular predictor of oocyte quality in FF were not able to identify substances that could be used as reliable markers of oocyte competence to fertilization, embryo development and pregnancy. In the last years, a well definite trend toward passing from the research of single molecular markers to more complex techniques that study all metabolites of FF has been observed. The metabolomic approach is a powerful tool to study biochemical predictors of oocyte quality in FF, but its application in this area is still at the beginning. This review provides an overview of the current knowledge about the biochemical predictors of oocyte quality in FF, describing both the results coming from studies on single biochemical markers and those deriving from the most recent studies of metabolomics." @default.
- W1967090815 created "2016-06-24" @default.
- W1967090815 creator A5026222625 @default.
- W1967090815 creator A5040525039 @default.
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- W1967090815 creator A5042567304 @default.
- W1967090815 creator A5059352992 @default.
- W1967090815 creator A5079158864 @default.
- W1967090815 date "2009-05-04" @default.
- W1967090815 modified "2023-10-16" @default.
- W1967090815 title "Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics" @default.
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