Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969376635> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1969376635 endingPage "609" @default.
- W1969376635 startingPage "605" @default.
- W1969376635 abstract "Evidence is presented for the photochemical formation of singlet molecular oxygen (1O2) in air-saturated aqueous solutions of several sunscreen active ingredients using sunlight-range illumination. This is of significance because (1) 1O2 is known to be cytotoxic, and (2) there have been several reports of toxic effects associated with the use of some sunscreens; most notably, with p-aminobenzoic acid (PABA). Illuminated aqueous solutions of PABA, 2-ethylhexyl p-(dimethylamino)benzate (ODPABA), 2-hydroxy-4-methoxybenzophenone (BZ3), 2,2'-dihydroxy-4-methoxybenzophenone (BZ8), 2-ethylhexyl 2-cyano-3,3-diphenylacrylate (OCR), 2-ethylhexyl p-methoxycinnamate (OMC), and 2-ethylhexyl salicylate (OCS) were evaluated individually for 1O2 formation. Furfuryl alcohol (FFA), a well-known chemical trap for 1O2, was added to each of the aqueous sunscreen solutions. The FFA was consumed when solutions of PABA, ODPABA, OMC, and OCR were illuminated, but no loss of FFA other than by direct photolysis occurred in solutions of BZ3, BZ8, or OCS. There was also no significant loss of FFA in any of these solutions kept in the dark. Further evidence for the formation of 1O2 in illuminated aqueous sunscreen solutions is provided by the results of experiments in which individual solutions containing sunscreen active ingredients and FFA that were diluted with D2O exhibited an increased rate of FFA consumption while the addition of azide ion (N3-) reduced the rate of FFA consumption. Continuous sunlight-range illumination of aqueous PABA solutions produced significantly higher steady-state concentrations of 1O2 than in solutions containing any of the other sunscreen active ingredients evaluated. The substituted benzophenone compounds (BZ3 and BZ8) and the salicylate-based compound (OCS) not only appear to produce no 1O2, but they also appear to produce no other reactive oxidant species that are capable of consuming FFA. This indicates that BZ3, BZ8, and OCS may be peferable, from the standpoint of toxic oxidant formation, for use as sunscreen active ingredients when compared to the other compounds evaluated in this study." @default.
- W1969376635 created "2016-06-24" @default.
- W1969376635 creator A5015742703 @default.
- W1969376635 creator A5041302332 @default.
- W1969376635 creator A5087814817 @default.
- W1969376635 date "1996-01-01" @default.
- W1969376635 modified "2023-10-14" @default.
- W1969376635 title "Photochemical Formation of Singlet Molecular Oxygen in Illuminated Aqueous Solutions of Several Commercially Available Sunscreen Active Ingredients" @default.
- W1969376635 cites W1986669892 @default.
- W1969376635 cites W1988765421 @default.
- W1969376635 cites W2029657195 @default.
- W1969376635 doi "https://doi.org/10.1021/tx950197m" @default.
- W1969376635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8728505" @default.
- W1969376635 hasPublicationYear "1996" @default.
- W1969376635 type Work @default.
- W1969376635 sameAs 1969376635 @default.
- W1969376635 citedByCount "103" @default.
- W1969376635 countsByYear W19693766352012 @default.
- W1969376635 countsByYear W19693766352013 @default.
- W1969376635 countsByYear W19693766352014 @default.
- W1969376635 countsByYear W19693766352015 @default.
- W1969376635 countsByYear W19693766352016 @default.
- W1969376635 countsByYear W19693766352017 @default.
- W1969376635 countsByYear W19693766352018 @default.
- W1969376635 countsByYear W19693766352019 @default.
- W1969376635 countsByYear W19693766352020 @default.
- W1969376635 countsByYear W19693766352021 @default.
- W1969376635 countsByYear W19693766352022 @default.
- W1969376635 countsByYear W19693766352023 @default.
- W1969376635 crossrefType "journal-article" @default.
- W1969376635 hasAuthorship W1969376635A5015742703 @default.
- W1969376635 hasAuthorship W1969376635A5041302332 @default.
- W1969376635 hasAuthorship W1969376635A5087814817 @default.
- W1969376635 hasConcept C161790260 @default.
- W1969376635 hasConcept C178790620 @default.
- W1969376635 hasConcept C184651966 @default.
- W1969376635 hasConcept C185592680 @default.
- W1969376635 hasConcept C2777516457 @default.
- W1969376635 hasConcept C2780526948 @default.
- W1969376635 hasConcept C540031477 @default.
- W1969376635 hasConcept C75473681 @default.
- W1969376635 hasConceptScore W1969376635C161790260 @default.
- W1969376635 hasConceptScore W1969376635C178790620 @default.
- W1969376635 hasConceptScore W1969376635C184651966 @default.
- W1969376635 hasConceptScore W1969376635C185592680 @default.
- W1969376635 hasConceptScore W1969376635C2777516457 @default.
- W1969376635 hasConceptScore W1969376635C2780526948 @default.
- W1969376635 hasConceptScore W1969376635C540031477 @default.
- W1969376635 hasConceptScore W1969376635C75473681 @default.
- W1969376635 hasIssue "3" @default.
- W1969376635 hasLocation W19693766351 @default.
- W1969376635 hasLocation W19693766352 @default.
- W1969376635 hasOpenAccess W1969376635 @default.
- W1969376635 hasPrimaryLocation W19693766351 @default.
- W1969376635 hasRelatedWork W2001542914 @default.
- W1969376635 hasRelatedWork W2011591073 @default.
- W1969376635 hasRelatedWork W2123960173 @default.
- W1969376635 hasRelatedWork W2167066203 @default.
- W1969376635 hasRelatedWork W2356059151 @default.
- W1969376635 hasRelatedWork W2357145381 @default.
- W1969376635 hasRelatedWork W3090553516 @default.
- W1969376635 hasRelatedWork W3095777693 @default.
- W1969376635 hasRelatedWork W3177031053 @default.
- W1969376635 hasRelatedWork W4313404294 @default.
- W1969376635 hasVolume "9" @default.
- W1969376635 isParatext "false" @default.
- W1969376635 isRetracted "false" @default.
- W1969376635 magId "1969376635" @default.
- W1969376635 workType "article" @default.