FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972124669> ?p ?o ?g. }

• W1972124669 endingPage "202" @default.
• W1972124669 startingPage "193" @default.
• W1972124669 abstract "It has long been hypothesized that fibronectin (Fn) is essential to the function of the reticuloendothelial system (RES) and that the reversal of Fn deficiency in critically ill patients would result in a clinical benefit to these patients. Fn administration to deficient patients was postulated to improve the function of the RES, decrease the incidence of organ failure, sepsis and ultimately mortality. Over the past 15 years, several clinical studies have been performed to test these hypotheses. The initial anecdotal studies using cryoprecipitate (a plasma fraction enriched in Fn) revealed promising results but were neither controlled nor blinded. Further controlled studies were published utilizing both cryoprecipitate and purified Fn. Unfortunately, the great majority of authors found no beneficial effects of Fn administration in critically ill patients, in relation to incidence of organ failure, sepsis, or mortality. These results do not support the use of Fn in this setting. Fn utilization in wound healing has shown promising results in case reports. Although its role in wound healing is not yet fully delineated, initial reports with corneal wounds show a beneficial influence of Fn administration. Further studies are needed to determine the exact function(s) of Fn in a healing wound. Efficacy must still be shown in controlled clinical trials; dosing and administration regimens need to be elucidated." @default.
• W1972124669 created "2016-06-24" @default.
• W1972124669 creator A5021575066 @default.
• W1972124669 creator A5056200970 @default.
• W1972124669 date "1991-05-01" @default.
• W1972124669 modified "2023-09-27" @default.
• W1972124669 title "Current Status of Fibronectin in Transfusion Medicine: Focus on Clinical Studies" @default.
• W1972124669 cites W1845499283 @default.
• W1972124669 cites W189687390 @default.
• W1972124669 cites W1967194093 @default.
• W1972124669 cites W1967272259 @default.
• W1972124669 cites W1971516428 @default.
• W1972124669 cites W1974906611 @default.
• W1972124669 cites W1974977574 @default.
• W1972124669 cites W1975812322 @default.
• W1972124669 cites W1980229420 @default.
• W1972124669 cites W1981494523 @default.
• W1972124669 cites W1985101546 @default.
• W1972124669 cites W1993104510 @default.
• W1972124669 cites W1997472441 @default.
• W1972124669 cites W2005369874 @default.
• W1972124669 cites W2017889281 @default.
• W1972124669 cites W2018595617 @default.
• W1972124669 cites W2020852924 @default.
• W1972124669 cites W2024977802 @default.
• W1972124669 cites W2027264961 @default.
• W1972124669 cites W2028571799 @default.
• W1972124669 cites W2029155548 @default.
• W1972124669 cites W2030954845 @default.
• W1972124669 cites W2037817461 @default.
• W1972124669 cites W2038015819 @default.
• W1972124669 cites W2041591911 @default.
• W1972124669 cites W2046194221 @default.
• W1972124669 cites W2052031414 @default.
• W1972124669 cites W2052283297 @default.
• W1972124669 cites W2053106981 @default.
• W1972124669 cites W2057626056 @default.
• W1972124669 cites W2058965634 @default.
• W1972124669 cites W2065610663 @default.
• W1972124669 cites W2065876468 @default.
• W1972124669 cites W2065948470 @default.
• W1972124669 cites W2066433318 @default.
• W1972124669 cites W2069397414 @default.
• W1972124669 cites W2076036766 @default.
• W1972124669 cites W2078278323 @default.
• W1972124669 cites W2081205285 @default.
• W1972124669 cites W2082815255 @default.
• W1972124669 cites W2088611078 @default.
• W1972124669 cites W2094289334 @default.
• W1972124669 cites W2125258660 @default.
• W1972124669 cites W2133191346 @default.
• W1972124669 cites W2139629945 @default.
• W1972124669 cites W2144363851 @default.
• W1972124669 cites W2148326895 @default.
• W1972124669 cites W2268601939 @default.
• W1972124669 cites W2416891687 @default.
• W1972124669 cites W2419311140 @default.
• W1972124669 cites W2419597726 @default.
• W1972124669 cites W2421208417 @default.
• W1972124669 cites W2465216279 @default.
• W1972124669 cites W2895311457 @default.
• W1972124669 cites W4232098720 @default.
• W1972124669 cites W4250589130 @default.
• W1972124669 cites W4252167184 @default.
• W1972124669 cites W82180823 @default.
• W1972124669 cites W92489547 @default.
• W1972124669 doi "https://doi.org/10.1111/j.1423-0410.1991.tb00905.x" @default.
• W1972124669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1926827" @default.
• W1972124669 hasPublicationYear "1991" @default.
• W1972124669 type Work @default.
• W1972124669 sameAs 1972124669 @default.
• W1972124669 citedByCount "9" @default.
• W1972124669 crossrefType "journal-article" @default.
• W1972124669 hasAuthorship W1972124669A5021575066 @default.
• W1972124669 hasAuthorship W1972124669A5056200970 @default.
• W1972124669 hasBestOaLocation W19721246691 @default.
• W1972124669 hasConcept C120665830 @default.
• W1972124669 hasConcept C121332964 @default.
• W1972124669 hasConcept C126322002 @default.
• W1972124669 hasConcept C141071460 @default.
• W1972124669 hasConcept C1491633281 @default.
• W1972124669 hasConcept C177713679 @default.
• W1972124669 hasConcept C2777288759 @default.
• W1972124669 hasConcept C2778258694 @default.
• W1972124669 hasConcept C2778384902 @default.
• W1972124669 hasConcept C2779036427 @default.
• W1972124669 hasConcept C2780269544 @default.
• W1972124669 hasConcept C535046627 @default.
• W1972124669 hasConcept C54355233 @default.
• W1972124669 hasConcept C61511704 @default.
• W1972124669 hasConcept C71924100 @default.
• W1972124669 hasConcept C86492073 @default.
• W1972124669 hasConcept C86803240 @default.
• W1972124669 hasConceptScore W1972124669C120665830 @default.
• W1972124669 hasConceptScore W1972124669C121332964 @default.
• W1972124669 hasConceptScore W1972124669C126322002 @default.
• W1972124669 hasConceptScore W1972124669C141071460 @default.
• W1972124669 hasConceptScore W1972124669C1491633281 @default.

• next