Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974429536> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1974429536 endingPage "902" @default.
- W1974429536 startingPage "899" @default.
- W1974429536 abstract "α-Thujaplicin, a minor component of Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO), showed rather strong antifungal activity against seven kinds of plant-pathogenic fungi, their minimum inhibitory concentrations (MICs) being in the range of 12.0—50.0 μg/ml. α-Thujaplicin and hinokitiol (the major component of Aomori Hiba) also showed clear antibacterial activity against Legionella pneumophila SG 1 and L. pneumophila SG 3, and their MICs are in the range of 6.25—50 μg/ml. This compound showed strong insecticidal activity against Reticulitermes speratus [50%-lethal concentration (LC50): 0.02 g/m2], and it also had clear acaricidal activity against Dermatophagoides farinae (LC50: 0.66 g/m2). At 24 h after treatment, α-thujaplicin at 0.63 μg/ml inhibited the cell growth of murine P388 lymphocytic leukemia by 78%, and its cytotoxic activity at a concentration higher than 0.63 μg/ml was as high as that of vincristine, used as a positive control. On the other hand, the cytotoxic effect of α-thujaplicin at 0.63 μg/ml was weaker than that of vinblastine. In this respect, the strong cytotoxic effect of α-thujaplicin on murine P388 lymphocytic leukemia cell line should be emphasized, considering that it has recently been found to be low in toxicity to mice." @default.
- W1974429536 created "2016-06-24" @default.
- W1974429536 creator A5000862574 @default.
- W1974429536 creator A5004645203 @default.
- W1974429536 creator A5013932299 @default.
- W1974429536 creator A5042339850 @default.
- W1974429536 creator A5066217056 @default.
- W1974429536 creator A5070676345 @default.
- W1974429536 creator A5077215453 @default.
- W1974429536 creator A5079432428 @default.
- W1974429536 creator A5082784490 @default.
- W1974429536 creator A5086775003 @default.
- W1974429536 date "2004-01-01" @default.
- W1974429536 modified "2023-10-05" @default.
- W1974429536 title "Biological Activity of .ALPHA.-Thujaplicin, the Isomer of Hinokitiol" @default.
- W1974429536 cites W1963687774 @default.
- W1974429536 cites W1979679858 @default.
- W1974429536 cites W1981064215 @default.
- W1974429536 cites W1998432960 @default.
- W1974429536 cites W2045244347 @default.
- W1974429536 cites W2056290526 @default.
- W1974429536 cites W2101119429 @default.
- W1974429536 cites W2332495005 @default.
- W1974429536 cites W2334848090 @default.
- W1974429536 doi "https://doi.org/10.1248/bpb.27.899" @default.
- W1974429536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15187442" @default.
- W1974429536 hasPublicationYear "2004" @default.
- W1974429536 type Work @default.
- W1974429536 sameAs 1974429536 @default.
- W1974429536 citedByCount "33" @default.
- W1974429536 countsByYear W19744295362013 @default.
- W1974429536 countsByYear W19744295362014 @default.
- W1974429536 countsByYear W19744295362015 @default.
- W1974429536 countsByYear W19744295362016 @default.
- W1974429536 countsByYear W19744295362017 @default.
- W1974429536 countsByYear W19744295362021 @default.
- W1974429536 countsByYear W19744295362022 @default.
- W1974429536 countsByYear W19744295362023 @default.
- W1974429536 crossrefType "journal-article" @default.
- W1974429536 hasAuthorship W1974429536A5000862574 @default.
- W1974429536 hasAuthorship W1974429536A5004645203 @default.
- W1974429536 hasAuthorship W1974429536A5013932299 @default.
- W1974429536 hasAuthorship W1974429536A5042339850 @default.
- W1974429536 hasAuthorship W1974429536A5066217056 @default.
- W1974429536 hasAuthorship W1974429536A5070676345 @default.
- W1974429536 hasAuthorship W1974429536A5077215453 @default.
- W1974429536 hasAuthorship W1974429536A5079432428 @default.
- W1974429536 hasAuthorship W1974429536A5082784490 @default.
- W1974429536 hasAuthorship W1974429536A5086775003 @default.
- W1974429536 hasBestOaLocation W19744295361 @default.
- W1974429536 hasConcept C109316439 @default.
- W1974429536 hasConcept C154317977 @default.
- W1974429536 hasConcept C185592680 @default.
- W1974429536 hasConcept C202751555 @default.
- W1974429536 hasConcept C2779707156 @default.
- W1974429536 hasConcept C55493867 @default.
- W1974429536 hasConcept C86803240 @default.
- W1974429536 hasConcept C89423630 @default.
- W1974429536 hasConceptScore W1974429536C109316439 @default.
- W1974429536 hasConceptScore W1974429536C154317977 @default.
- W1974429536 hasConceptScore W1974429536C185592680 @default.
- W1974429536 hasConceptScore W1974429536C202751555 @default.
- W1974429536 hasConceptScore W1974429536C2779707156 @default.
- W1974429536 hasConceptScore W1974429536C55493867 @default.
- W1974429536 hasConceptScore W1974429536C86803240 @default.
- W1974429536 hasConceptScore W1974429536C89423630 @default.
- W1974429536 hasIssue "6" @default.
- W1974429536 hasLocation W19744295361 @default.
- W1974429536 hasLocation W19744295362 @default.
- W1974429536 hasOpenAccess W1974429536 @default.
- W1974429536 hasPrimaryLocation W19744295361 @default.
- W1974429536 hasRelatedWork W1551339714 @default.
- W1974429536 hasRelatedWork W1892306976 @default.
- W1974429536 hasRelatedWork W2008095939 @default.
- W1974429536 hasRelatedWork W2024203776 @default.
- W1974429536 hasRelatedWork W2029611001 @default.
- W1974429536 hasRelatedWork W2049591727 @default.
- W1974429536 hasRelatedWork W2072827207 @default.
- W1974429536 hasRelatedWork W2100079462 @default.
- W1974429536 hasRelatedWork W2104363897 @default.
- W1974429536 hasRelatedWork W2166496668 @default.
- W1974429536 hasVolume "27" @default.
- W1974429536 isParatext "false" @default.
- W1974429536 isRetracted "false" @default.
- W1974429536 magId "1974429536" @default.
- W1974429536 workType "article" @default.