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- W1976809752 abstract "To assess work productivity and daily activity impairment among irritable bowel syndrome with constipation (IBS-C) patients in the United States. IBS-C patients aged ≥18 years with continuous medical and pharmacy benefit eligibility (03/01/2011–02/28/2013) were identified from claims in the HealthCore Integrated Research Database and invited to complete a cross-sectional patient survey. Survey questions based on modified Rome III criteria confirmed IBS-C claims-based diagnoses. Patients who met both claims-based and Rome criteria completed the full survey, including the Work Productivity and Activity Impairment Questionnaire: General Health (WPAI: GH), which assessed the impact of general health problems on patients’ ability to work and function. WPAI: GH scores for absenteeism (work hours missed), presenteeism (lost productivity at work), and overall work productivity loss (absenteeism + presenteeism) over the previous week were calculated for employed respondents; daily activity impairment (functional impairment) was computed for all respondents. Follow-up questions adapted from the WPAI: GH evaluated work and activity impairment due to IBS-C. Scores are expressed as percentages, with higher percentages indicating greater impairment and less productivity. Indirect costs were calculated based on overall work productivity loss due to IBS-C using the human capital method. Of 53 respondents (mean age: 40±15 years; 84.9% female), 35 were employed. Absenteeism averaged 10.6%, presenteeism averaged 37.4%, overall work productivity loss averaged 39.3%, and daily activity impairment averaged 45.7% due to general health problems over the past week. Of this, 7.5%, 21.5%, 23.8%, and 14.2% was attributed to IBS-C, respectively. The economic cost due to lost productivity attributable to IBS-C was estimated at $155±$321 USD per employed patient/week. IBS-C–related impairment at work and in daily activities represents a significant burden for patients and employers. Treatments that effectively manage IBS-C symptoms may represent cost savings in the form of avoided work productivity losses associated with IBS-C." @default.
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- W1976809752 date "2014-11-01" @default.
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- W1976809752 title "Impact Of Irritable Bowel Syndrome With Constipation On Work Productivity And Daily Activity Among Commercially Insured Patients In The United States" @default.
- W1976809752 doi "https://doi.org/10.1016/j.jval.2014.08.839" @default.
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