FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977568638> ?p ?o ?g. }

• W1977568638 endingPage "383" @default.
• W1977568638 startingPage "376" @default.
• W1977568638 abstract "There are no reliable markers useful to predict the onset or the evolution of chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (HSCT), although several candidate biomarkers have been identified from limited hypothesis-driven studies. In this study we evaluated 14 patients who received a reduced intensity conditioning HSCT. Seven patients had cGVHD, whereas 7 never developed cGVHD during the period of observation. The expression of 114 cytokines in immunoselected cell populations was explored by microarray analysis and 11 cytokines were selected for further evaluation by real-time PCR. Differential gene expression measurements showed a significant up-regulation for INFγ (interferon, gamma) in CD8+ and for TNFSF3 (tumor necrosis factor superfamily, member 3) and for TNFSF10 (tumor necrosis factor superfamily, member 10) in CD14+ cell population when comparing cGVHD with control samples. The expression levels were significantly decreased for TNFSF10 in CD8+ cell population and for TNFSF12 (tumor necrosis factor superfamily, member 12) and for PDGFβ (platelet-derived growth factor, beta) in CD4+. Our data seem to suggest that different immune populations can play a role in cGVHD pathogenesis and the early detection of gene expression profile in these patients could be useful in the monitoring of GVHD. We hypothesized that PDGFβ down-regulation could represent a negative feedback to compensate for enhanced expression of its receptor recently reported." @default.
• W1977568638 created "2016-06-24" @default.
• W1977568638 creator A5005308876 @default.
• W1977568638 creator A5017395429 @default.
• W1977568638 creator A5018631492 @default.
• W1977568638 creator A5022330993 @default.
• W1977568638 creator A5040503651 @default.
• W1977568638 creator A5045635519 @default.
• W1977568638 creator A5046312032 @default.
• W1977568638 creator A5053762786 @default.
• W1977568638 creator A5066720467 @default.
• W1977568638 creator A5075520151 @default.
• W1977568638 creator A5084455514 @default.
• W1977568638 creator A5088147792 @default.
• W1977568638 date "2011-03-01" @default.
• W1977568638 modified "2023-10-16" @default.
• W1977568638 title "Gene expression profile of cytokines in patients with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation with reduced conditioning" @default.
• W1977568638 cites W1530764705 @default.
• W1977568638 cites W1940480041 @default.
• W1977568638 cites W1963678500 @default.
• W1977568638 cites W1969194297 @default.
• W1977568638 cites W1985088435 @default.
• W1977568638 cites W2008548657 @default.
• W1977568638 cites W2017412050 @default.
• W1977568638 cites W2024402262 @default.
• W1977568638 cites W2036872637 @default.
• W1977568638 cites W2038530621 @default.
• W1977568638 cites W2041548911 @default.
• W1977568638 cites W2042671718 @default.
• W1977568638 cites W2057514737 @default.
• W1977568638 cites W2061061720 @default.
• W1977568638 cites W2061800382 @default.
• W1977568638 cites W2063753518 @default.
• W1977568638 cites W2067243586 @default.
• W1977568638 cites W2077627992 @default.
• W1977568638 cites W2078603776 @default.
• W1977568638 cites W2093298135 @default.
• W1977568638 cites W2120428769 @default.
• W1977568638 cites W2140143467 @default.
• W1977568638 cites W2146331182 @default.
• W1977568638 cites W2165524100 @default.
• W1977568638 cites W2167332796 @default.
• W1977568638 cites W2400716750 @default.
• W1977568638 cites W2618073389 @default.
• W1977568638 cites W4233873287 @default.
• W1977568638 doi "https://doi.org/10.1016/j.cyto.2010.12.008" @default.
• W1977568638 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21211989" @default.
• W1977568638 hasPublicationYear "2011" @default.
• W1977568638 type Work @default.
• W1977568638 sameAs 1977568638 @default.
• W1977568638 citedByCount "13" @default.
• W1977568638 countsByYear W19775686382012 @default.
• W1977568638 countsByYear W19775686382013 @default.
• W1977568638 countsByYear W19775686382014 @default.
• W1977568638 countsByYear W19775686382016 @default.
• W1977568638 countsByYear W19775686382017 @default.
• W1977568638 countsByYear W19775686382020 @default.
• W1977568638 crossrefType "journal-article" @default.
• W1977568638 hasAuthorship W1977568638A5005308876 @default.
• W1977568638 hasAuthorship W1977568638A5017395429 @default.
• W1977568638 hasAuthorship W1977568638A5018631492 @default.
• W1977568638 hasAuthorship W1977568638A5022330993 @default.
• W1977568638 hasAuthorship W1977568638A5040503651 @default.
• W1977568638 hasAuthorship W1977568638A5045635519 @default.
• W1977568638 hasAuthorship W1977568638A5046312032 @default.
• W1977568638 hasAuthorship W1977568638A5053762786 @default.
• W1977568638 hasAuthorship W1977568638A5066720467 @default.
• W1977568638 hasAuthorship W1977568638A5075520151 @default.
• W1977568638 hasAuthorship W1977568638A5084455514 @default.
• W1977568638 hasAuthorship W1977568638A5088147792 @default.
• W1977568638 hasConcept C109159458 @default.
• W1977568638 hasConcept C126322002 @default.
• W1977568638 hasConcept C167672396 @default.
• W1977568638 hasConcept C17991360 @default.
• W1977568638 hasConcept C203014093 @default.
• W1977568638 hasConcept C2777408962 @default.
• W1977568638 hasConcept C2779972918 @default.
• W1977568638 hasConcept C2780942790 @default.
• W1977568638 hasConcept C28328180 @default.
• W1977568638 hasConcept C2908647359 @default.
• W1977568638 hasConcept C2911091166 @default.
• W1977568638 hasConcept C502942594 @default.
• W1977568638 hasConcept C54355233 @default.
• W1977568638 hasConcept C71924100 @default.
• W1977568638 hasConcept C86803240 @default.
• W1977568638 hasConcept C8891405 @default.
• W1977568638 hasConcept C99454951 @default.
• W1977568638 hasConceptScore W1977568638C109159458 @default.
• W1977568638 hasConceptScore W1977568638C126322002 @default.
• W1977568638 hasConceptScore W1977568638C167672396 @default.
• W1977568638 hasConceptScore W1977568638C17991360 @default.
• W1977568638 hasConceptScore W1977568638C203014093 @default.
• W1977568638 hasConceptScore W1977568638C2777408962 @default.
• W1977568638 hasConceptScore W1977568638C2779972918 @default.
• W1977568638 hasConceptScore W1977568638C2780942790 @default.
• W1977568638 hasConceptScore W1977568638C28328180 @default.
• W1977568638 hasConceptScore W1977568638C2908647359 @default.
• W1977568638 hasConceptScore W1977568638C2911091166 @default.

• next