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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985016739> ?p ?o ?g. }

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• W1985016739 abstract "We have expressed fragments of the cDNA coding for mature human interleukin-1α(hIL-1α) in Saccharomyces cerevisiae. Mature hIL-1α contains one potential N-linked glycosylation site that is not recognized in mammalian cells. Translational fusions to either one of three yeast signal sequences resulted in secretion of bioactive, N-glycosylated hIL-1α. The extent of glycosylation was significantly reduced using the α-factor signal sequence, which itself contains three N-linked glycosylation sites known to be core glycosylated. N-glycosylation has no effect on biological specific activity." @default.
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• W1985016739 date "1990-04-01" @default.
• W1985016739 modified "2023-10-10" @default.
• W1985016739 title "Secretion of N-glycosylated human recombinant interleukin-1α in Saccharomyces cerevisiae" @default.
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• W1985016739 doi "https://doi.org/10.1016/0378-1119(90)90048-v" @default.
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