FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987220098> ?p ?o ?g. }

• W1987220098 endingPage "86" @default.
• W1987220098 startingPage "79" @default.
• W1987220098 abstract "Human African trypanosomiasis is characterised by an important clinical diversity. Although Trypanosoma brucei gambiense field stocks isolated from patients in the same focus did not exhibit apparent genetic variability, they showed marked differences in terms of virulence (capacity to multiply inside a host) and pathogenicity (ability of producing mortality) in experimental murine infections. Two strains exhibiting opposite pathogenic and virulence properties in mouse were further investigated through their host–parasite interactions. In vitro, parasite bloodstream forms or soluble factors (or secretome) from both strains induced macrophage arginase as a function of their virulence. Arginase expression, a hallmark of macrophage alternative activation pathway, favours trypanosome bloodstream forms development. Moreover, a comparative proteomic study of the trypanosome stocks' secretomes evidenced both a differential expression of common molecules and the existence of stock specific molecules. This highlighted the potential involvement of the differential expression of the same genome in the diverse infectious properties of trypanosomes." @default.
• W1987220098 created "2016-06-24" @default.
• W1987220098 creator A5023837946 @default.
• W1987220098 creator A5034691946 @default.
• W1987220098 creator A5036723132 @default.
• W1987220098 creator A5044373961 @default.
• W1987220098 creator A5068230324 @default.
• W1987220098 creator A5069878301 @default.
• W1987220098 creator A5079517031 @default.
• W1987220098 creator A5082970632 @default.
• W1987220098 creator A5084051743 @default.
• W1987220098 creator A5089089482 @default.
• W1987220098 date "2008-01-01" @default.
• W1987220098 modified "2023-10-15" @default.
• W1987220098 title "Virulence and pathogenicity patterns of Trypanosoma brucei gambiense field isolates in experimentally infected mouse: differences in host immune response modulation by secretome and proteomics" @default.
• W1987220098 cites W1490103513 @default.
• W1987220098 cites W1970144610 @default.
• W1987220098 cites W1971807222 @default.
• W1987220098 cites W1976400620 @default.
• W1987220098 cites W1976744415 @default.
• W1987220098 cites W2015141049 @default.
• W1987220098 cites W2017446643 @default.
• W1987220098 cites W2017685664 @default.
• W1987220098 cites W2022818789 @default.
• W1987220098 cites W2025521783 @default.
• W1987220098 cites W2027110135 @default.
• W1987220098 cites W2029262008 @default.
• W1987220098 cites W2038147373 @default.
• W1987220098 cites W2055329508 @default.
• W1987220098 cites W2059927435 @default.
• W1987220098 cites W2078174957 @default.
• W1987220098 cites W2080184093 @default.
• W1987220098 cites W2099616490 @default.
• W1987220098 cites W2101998831 @default.
• W1987220098 cites W2102155970 @default.
• W1987220098 cites W2104032278 @default.
• W1987220098 cites W2122053924 @default.
• W1987220098 cites W2124381019 @default.
• W1987220098 cites W2128922744 @default.
• W1987220098 cites W2152242329 @default.
• W1987220098 cites W2153438004 @default.
• W1987220098 cites W2156559790 @default.
• W1987220098 cites W2157156641 @default.
• W1987220098 cites W2417145771 @default.
• W1987220098 doi "https://doi.org/10.1016/j.micinf.2007.10.008" @default.
• W1987220098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18068387" @default.
• W1987220098 hasPublicationYear "2008" @default.
• W1987220098 type Work @default.
• W1987220098 sameAs 1987220098 @default.
• W1987220098 citedByCount "56" @default.
• W1987220098 countsByYear W19872200982012 @default.
• W1987220098 countsByYear W19872200982013 @default.
• W1987220098 countsByYear W19872200982014 @default.
• W1987220098 countsByYear W19872200982015 @default.
• W1987220098 countsByYear W19872200982016 @default.
• W1987220098 countsByYear W19872200982017 @default.
• W1987220098 countsByYear W19872200982018 @default.
• W1987220098 countsByYear W19872200982019 @default.
• W1987220098 countsByYear W19872200982020 @default.
• W1987220098 countsByYear W19872200982021 @default.
• W1987220098 countsByYear W19872200982023 @default.
• W1987220098 crossrefType "journal-article" @default.
• W1987220098 hasAuthorship W1987220098A5023837946 @default.
• W1987220098 hasAuthorship W1987220098A5034691946 @default.
• W1987220098 hasAuthorship W1987220098A5036723132 @default.
• W1987220098 hasAuthorship W1987220098A5044373961 @default.
• W1987220098 hasAuthorship W1987220098A5068230324 @default.
• W1987220098 hasAuthorship W1987220098A5069878301 @default.
• W1987220098 hasAuthorship W1987220098A5079517031 @default.
• W1987220098 hasAuthorship W1987220098A5082970632 @default.
• W1987220098 hasAuthorship W1987220098A5084051743 @default.
• W1987220098 hasAuthorship W1987220098A5089089482 @default.
• W1987220098 hasConcept C104317684 @default.
• W1987220098 hasConcept C136764020 @default.
• W1987220098 hasConcept C159047783 @default.
• W1987220098 hasConcept C164007495 @default.
• W1987220098 hasConcept C191942190 @default.
• W1987220098 hasConcept C202751555 @default.
• W1987220098 hasConcept C2777468819 @default.
• W1987220098 hasConcept C2778143080 @default.
• W1987220098 hasConcept C2778375072 @default.
• W1987220098 hasConcept C2778792689 @default.
• W1987220098 hasConcept C2779244956 @default.
• W1987220098 hasConcept C2779502636 @default.
• W1987220098 hasConcept C41008148 @default.
• W1987220098 hasConcept C46111723 @default.
• W1987220098 hasConcept C515207424 @default.
• W1987220098 hasConcept C54355233 @default.
• W1987220098 hasConcept C60987743 @default.
• W1987220098 hasConcept C71928629 @default.
• W1987220098 hasConcept C86803240 @default.
• W1987220098 hasConcept C8891405 @default.
• W1987220098 hasConcept C89423630 @default.
• W1987220098 hasConceptScore W1987220098C104317684 @default.
• W1987220098 hasConceptScore W1987220098C136764020 @default.
• W1987220098 hasConceptScore W1987220098C159047783 @default.
• W1987220098 hasConceptScore W1987220098C164007495 @default.
• W1987220098 hasConceptScore W1987220098C191942190 @default.

• next