FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990505809> ?p ?o ?g. }

• W1990505809 abstract "The Nile Blue chromophore was incorporated into oligonucleotides using “click” chemistry for the postsynthetic modification of oligonucleotides. These were synthesized using DNA building block 3 bearing an alkyne group and reacted with the azide 4 . ( R )-3-amino-1,2-propanediol was applied as the linker between the phosphodiester bridges. Two sets of DNA duplexes were prepared. One set carried the chromophore in an A-T environment, the second set in a G-C environment. Both were characterized by optical spectroscopy. Sequence-dependent fluorescence quenching was applied as a sensitive tool to compare the stacking interactions with respect to the chirality of the acyclic linker attachment. The results were compared to recent results from duplexes that carried the Nile Blue label in a sequentially and structurally identical context, except for the opposite chirality of the linker (( S )-3-amino-1,2-propandiol). Only minor, negligible differences were observed. Melting temperatures, UV–vis absorption spectra together with fluorescence quenching data indicate that Nile Blue stacks perfectly between the adjacent base pairs regardless of whether it has been attached via an S - or R -configured linker. This result was supported by geometrically optimized DNA models." @default.
• W1990505809 created "2016-06-24" @default.
• W1990505809 creator A5020530834 @default.
• W1990505809 creator A5064869630 @default.
• W1990505809 creator A5069614386 @default.
• W1990505809 creator A5079684636 @default.
• W1990505809 date "2010-02-09" @default.
• W1990505809 modified "2023-09-30" @default.
• W1990505809 title "Synthetic incorporation of Nile Blue into DNA using 2′-deoxyriboside substitutes: Representative comparison of (<i>R</i>)- and (<i>S</i>)-aminopropanediol as an acyclic linker" @default.
• W1990505809 cites W1970131031 @default.
• W1990505809 cites W1970371150 @default.
• W1990505809 cites W1974375844 @default.
• W1990505809 cites W1974965694 @default.
• W1990505809 cites W1977762520 @default.
• W1990505809 cites W1979238507 @default.
• W1990505809 cites W1988806669 @default.
• W1990505809 cites W2002805769 @default.
• W1990505809 cites W2002999950 @default.
• W1990505809 cites W2004517234 @default.
• W1990505809 cites W2008819037 @default.
• W1990505809 cites W2010741413 @default.
• W1990505809 cites W2010934396 @default.
• W1990505809 cites W2011218110 @default.
• W1990505809 cites W2017588168 @default.
• W1990505809 cites W2022855754 @default.
• W1990505809 cites W2026198319 @default.
• W1990505809 cites W2035191160 @default.
• W1990505809 cites W2049044382 @default.
• W1990505809 cites W2049117254 @default.
• W1990505809 cites W2052761897 @default.
• W1990505809 cites W2060181267 @default.
• W1990505809 cites W2064633591 @default.
• W1990505809 cites W2071631514 @default.
• W1990505809 cites W2073284952 @default.
• W1990505809 cites W2074577934 @default.
• W1990505809 cites W2078395738 @default.
• W1990505809 cites W2089106733 @default.
• W1990505809 cites W2090040397 @default.
• W1990505809 cites W2097340418 @default.
• W1990505809 cites W2112349904 @default.
• W1990505809 cites W2114733818 @default.
• W1990505809 cites W2123714202 @default.
• W1990505809 cites W2126526871 @default.
• W1990505809 cites W2130796369 @default.
• W1990505809 cites W2135817740 @default.
• W1990505809 cites W2137458512 @default.
• W1990505809 cites W2141437322 @default.
• W1990505809 cites W2144169173 @default.
• W1990505809 cites W2144222499 @default.
• W1990505809 cites W2146910635 @default.
• W1990505809 cites W2151709132 @default.
• W1990505809 cites W2329820975 @default.
• W1990505809 cites W4234422402 @default.
• W1990505809 doi "https://doi.org/10.3762/bjoc.6.13" @default.
• W1990505809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2871008" @default.
• W1990505809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20485595" @default.
• W1990505809 hasPublicationYear "2010" @default.
• W1990505809 type Work @default.
• W1990505809 sameAs 1990505809 @default.
• W1990505809 citedByCount "8" @default.
• W1990505809 countsByYear W19905058092012 @default.
• W1990505809 countsByYear W19905058092013 @default.
• W1990505809 countsByYear W19905058092014 @default.
• W1990505809 countsByYear W19905058092015 @default.
• W1990505809 countsByYear W19905058092018 @default.
• W1990505809 countsByYear W19905058092022 @default.
• W1990505809 crossrefType "journal-article" @default.
• W1990505809 hasAuthorship W1990505809A5020530834 @default.
• W1990505809 hasAuthorship W1990505809A5064869630 @default.
• W1990505809 hasAuthorship W1990505809A5069614386 @default.
• W1990505809 hasAuthorship W1990505809A5079684636 @default.
• W1990505809 hasBestOaLocation W19905058091 @default.
• W1990505809 hasConcept C111919701 @default.
• W1990505809 hasConcept C121332964 @default.
• W1990505809 hasConcept C121745418 @default.
• W1990505809 hasConcept C129312508 @default.
• W1990505809 hasConcept C151730666 @default.
• W1990505809 hasConcept C178790620 @default.
• W1990505809 hasConcept C185581394 @default.
• W1990505809 hasConcept C185592680 @default.
• W1990505809 hasConcept C192468462 @default.
• W1990505809 hasConcept C21951064 @default.
• W1990505809 hasConcept C2779343474 @default.
• W1990505809 hasConcept C2780557392 @default.
• W1990505809 hasConcept C33347731 @default.
• W1990505809 hasConcept C41008148 @default.
• W1990505809 hasConcept C552990157 @default.
• W1990505809 hasConcept C55493867 @default.
• W1990505809 hasConcept C62520636 @default.
• W1990505809 hasConcept C71240020 @default.
• W1990505809 hasConcept C75473681 @default.
• W1990505809 hasConcept C8010536 @default.
• W1990505809 hasConcept C86803240 @default.
• W1990505809 hasConcept C91881484 @default.
• W1990505809 hasConceptScore W1990505809C111919701 @default.
• W1990505809 hasConceptScore W1990505809C121332964 @default.
• W1990505809 hasConceptScore W1990505809C121745418 @default.
• W1990505809 hasConceptScore W1990505809C129312508 @default.
• W1990505809 hasConceptScore W1990505809C151730666 @default.
• W1990505809 hasConceptScore W1990505809C178790620 @default.

• next