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• W1991214921 abstract "Clinical & Experimental AllergyVolume 25, Issue 7 p. 582-585 Free Access Nasal polyps—a model of chronic respiratory mucosal inflammation R. Djukanovic, R. Djukanovic Immunopharmacology Group, University Medicine, Centre Block, Level D, Southampton General Hospital, Southampton SO 16 6 YD, UKSearch for more papers by this author R. Djukanovic, R. Djukanovic Immunopharmacology Group, University Medicine, Centre Block, Level D, Southampton General Hospital, Southampton SO 16 6 YD, UKSearch for more papers by this author First published: July 1995 https://doi.org/10.1111/j.1365-2222.1995.tb01104.xCitations: 14AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Ruhno J, Howie M, Anderson M. et al. The increased numbers of epithelial mast cells in nasal polyps and adjacent turbinates is not allergy-dependent. Allergy 1990; 45: 370– 4. 2 Wladislavosky-Waserman P, Kern EB, Holley KE, Eisen-brey AB, Gleich GJ. Epithelial damage in nasal polyps. Clin Allergy 1984; 14: 241– 7. 3 Cauna N, Hinderer KH, Manzetti GW, Swanson EW. Fine structure of nasal polyps. Ann Otol 1972; 81: 41– 58. 4 Oppenheimer EH, Rosenstein BJ. Differential pathology of nasal polyps in cystic fibrosis and atopy. Lab Invest 1979; 40: 445– 9. 5 Djukanovic R, Roche WR, Wilson JW et al. Mucosal inflammation in asthma. State of the Art. Am Rev Respir Dis 1990; 142: 434– 57. 6 Rubbia-Brandt L, Sappino A, Gabbiani G. Locally applied GM-CSF induces the accumulation of a-smooth muscle actin containing fibroblasts. Virchows Archiv 1991; 60: 73– 82. 7 Wong DTW, Weller PF, Galli SJ et al. Human eosinophils express transforming growth factor α. J Exp Med 1990; 172: 673– 81. 8 Ohno I, Lea RG, Flanders KC et al. Eosinophils in chronically inflamed human upper airway tissue express transforming growth factor β1 gene (TGFβ1). J Clin Invest 1992; 89: 1662– 8. 9 Jordana M, Dolovich, Ohno I et al. Nasal polyposis: a model for chronic inflammation. In: WB Busse, ST Holgate, eds. Asthma and rhinitis. Boston : Blackwell Scientific Publications, 1995: 156– 64. 10 Elovic A, Wong DTW, Weller PF, Matossian K, Galli SJ. Expression of transforming growth factors-α and β1 messenger RNA and product by eosinophils in nasal polyps. J Allergy Clin Immunol 1994; 93: 864– 9. 11 Hamid Q, Barkans J, Meng Q et al. Human eosinophils synthesize and secrete interleukin-6 in vitro. Blood 1992; 80: 1496– 501. 12 Tai P-C, Sun L, Spry CJF. Effects of IL-5, granulocyte/ macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro. Clin Exp Immunol 1991; 85: 312– 6. 13 Desreumaux P, Janin A, Colombel JF et al. Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease. J Exp Med 1992; 175: 293– 6. 14 Moqbel R, Hamid Q, Ying S et al. Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony-stimulating factor in activated human eosinophils. J Exp Med 1991; 174: 749– 52. 15 Kita H, Ohnishi T, Okubo Y et al. Granulocyte/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils. J Exp Med 1991; 174: 745– 8. 16 Rothenberg ME, Owen WF Jr, Silberstein DS et al. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest 1988; 81: 1986– 92. 17 Slavin RG. Allergy is not a significant cause of nasal polyps. Arch Otolaryngol Head Neck Surg 1992; 118: 343– 6. 18 Lin C-M, Shun C-T, Hsu M-M. Lymphocytes subsets and antigen-specific IgE antibody in nasal polyp. Ann Allergy 1994; 72: 19– 24. 19 Xaubet A, Mullol J, Lopez E et al. Comparison of the role of nasal polyp and normal nasal mucosal epithelial cells on in vitro eosinophil survival. Mediation by GM-CSF and inhibition by dexamethasone. Clin Exp Allergy 1994; 24: 307– 17. 20 Devalia JL, Campbell AM, Sapsford RJ et al. Effect of nitrogen diodide on synthesis of cytokines expressed by human bronchial epithelial cells in vitro. Am J Resp Cell Mol Biol 1993; 9: 271– 8. 21 Cox G, Ohtoshi T, Vancheri C et al. Promotion of eosinophil survival by human bronchial epithelial cells and its modulation by steroids. Am J Resp Cell Mol Biol 1991; 41: 525– 31. 22 Kaliner M, Wasserman SI, Austen KF. Immunologic release of chemical mediators from human nasal polyps. N Eng J Med 1973, 289: 277– 81. 23 Ohno I, Lea R, Finotto S. et al. Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis. Am J Respir Cell Mol Biol 1991; 5: 505– 10. 24 Becker S, Koren HS, Henke DC. Interleukin-8 expression in normal nasal epithelium and its modulation by infection with respiratory syncytial virus and cytokines tumor necrosis factor, interleukin-1, and interleukin-6. Am J Resp Cell Mol Biol 1993; 8: 20– 7. 25 Mullol J, Xaubet A, Gaya A et al. Cytokine gene expression and release from epithelial cells. A comparison study between healthy nasal mucosa and nasal polyps. Clin Exp Allergy 1995; 25: 606– 14. 26 Fujisawa T, Abu-Ghazaleh R, Kita H, Sanderson CJ, Gleich GJ. Regulatory effect of cytokines on eosinophil degranulation. J Immunol 1990; 144: 642– 6. 27 Silberstein DS, Owen WF, Gasson JC et al. Enhancement of human eosinophil cytotoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte-macrophage colony-stimulating factor. J Immunol 1986; 137: 3290– 4. 28 Broide DH, Lotz M, Cuomo AJ et al. Cytokines in symptomatic asthma airways. J Allergy Clin Immunol 1992; 89: 958– 67. 29 Bentley AM, Meng Q, Robinson DS et al. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am J Resp Cell Mol Biol 1993; 8: 35– 42. 30 Robinson D, Hamid Q, Bentley A et al. Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993; 92: 313– 24. 31 Kato M, Liu MC, Stealey BA et al. Production of granu-locyte/macrophage colony-stimulating factor in human airways during allergen-induced late-phase reactions in atopic subjects. Lymph Cyto Res 1992; 11: 287– 92. 32 Bruijnzeel PLB, Kujiper PHM, Kapp A et al. The involvement of eosinophils in the patch test reaction to aeroaller-gens in atopic dermatitis: its relevance for the pathogenesis of atopic dermatitis. Clin Exp Allergy 1993; 23: 97– 109. 33 Sehmi R, Cromwell O, Wardlaw AJ, Moqbel R, Kay AB. Interleukin-8 is a chemo-attractant for eosinophils purified from subjects with a blood eosinophilia but not from normal healthy subjects. Clin Exp Allergy 1993; 23: 1027– 36. 34 Shute J, Lindley, Peichl P et al. Mucosal IgA is an important moderator of eosinophil migratory responses to tissue-derived chemoattractants. Int Archiv Allergy Immunol in press. 35 Walker C, Bauer W, Braun RK et al. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia. Am J Respir Crit Care Med 1994; 150: 1038– 48. Citing Literature Volume25, Issue7July 1995Pages 582-585 ReferencesRelatedInformation" @default.
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