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• W1994595500 abstract "Two 19-base-pair oligodeoxynucleotides, analogues of one of the operators which specifically bind the repressor protein in the regulatory part of the transposon Tn10 tetracycline-resistance (tet) determinant, have been studied by 1H-NMR spectroscopy. The analogues contain a mismatch in the central base pair of the double helix (T.T or A.A). The imino protons have been assigned to the base pairs by one-dimensional NOE measurements, and the thermally induced transition from the duplex to the single strand has been followed. The cytidine amino resonances have been assigned by means of two-dimensional NOE spectroscopy in H2O. Two-dimensional phase-sensitive NOE and magnitude-correlated spectra have been recorded in 2H2O; all nonexchangeable protons, with the exception of some of H5′, H5” protons, have been assigned. The NMR data made it possible to carry out a qualitative analysis of the structures of both oligodeoxynucleotides. The general structures close to B-DNA, show irregularities in the mismatch areas." @default.
• W1994595500 created "2016-06-24" @default.
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• W1994595500 date "1987-12-01" @default.
• W1994595500 modified "2023-09-27" @default.
• W1994595500 title "One- and two-dimensional 1H-NMR investigations of two 19-base-pair analogues of the tet operator" @default.
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• W1994595500 doi "https://doi.org/10.1111/j.1432-1033.1987.tb13651.x" @default.
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