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- W1997291484 abstract "AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract The synthesis of two 125I-labeled trisubstituted aromatic melatonergic agents is reported. N-[[2-[125I]iodo-5-methoxyphenyl)-1R, 2R-cyclopropyl]methyl] butanamide was prepared from the corresponding thallium salt and Na 125I in radiochemical yields of 13–45% (n = 3). High performance liquid chromatography separation of the two resulting radioiodinated isomers (8:2) from each other and the parent compound required the use of two different columns run in series. Synthesis of N-[[2-[125I]iodo-5-fluorophenyl)-1R, 2R-cyclopropyl]methyl] butanamide was prepared from the corresponding trimethylstannane precursor in radiochemical yields consistently in the range of 60–65% (n = 6). Copyright © 2002 John Wiley & Sons, Ltd. Citing Literature Volume45, Issue1115 October 2002Pages 987-994 RelatedInformation" @default.
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- W1997291484 title "Synthesis of radio-iodinated melatonergic agents" @default.
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