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- W1998759508 abstract "In their review of the recent surge in new examples of mono-allelically expressed genes in mammals, Ohlsson et al.1 Ohlsson R. et al. Monoallelic expression: ‘there can only be one’. Trends Genet. 1998; 14: 435-438 Abstract Full Text Full Text PDF PubMed Scopus (63) Google Scholar write: ‘The reason that the list of genes that display the peculiar property to express only one of the parental alleles are dominated by mammalian genes might reflect an emphasis on particular model systems, rather than a true difference between mammals and other phylogenetic groups.’ We would like to point out that simple organisms, such as bacteria, fungi and protozoa, have worked on methods for allelic exclusion long before mammals entered the scene. Some of these methods require transposition of alleles into a single expression site, but others involve allele selection at the transcriptional level that is comparable to the choices made by mammals practising mono-allelic gene expression 2 Borst P. Molecular genetics of antigenic variation. Immunol. Today. 1991; 12: A29-A33 Abstract Full Text PDF PubMed Scopus (91) Google Scholar , 3 Borst P. et al. Mechanisms of antigenic variation in African trypanosomes. Behring Inst. Mitt. 1997; 99: 1-15 PubMed Google Scholar ." @default.
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- W1998759508 title "Mono-allelic expression of genes in simple eukaryotes" @default.
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- W1998759508 doi "https://doi.org/10.1016/s0168-9525(98)01680-1" @default.
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