Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000319746> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2000319746 endingPage "74" @default.
- W2000319746 startingPage "61" @default.
- W2000319746 abstract "A sublethal dose of botulinum toxin was injected into the calf muscles of one leg in mice and caused paralysis of those muscles within 24 hr. Recovery from paralysis took place after several weeks. Electron-microscopic studies were made of muscle fibres of soleus (a “slow” muscle) and of the superficial part of gastrocnemius (composed of “fast” fibres) from animals surviving from 4 days to 33 weeks after the injection of toxin. Muscle fibres from both regions became atrophied during the first 2–3 weeks and folds of redundant basement membrane became dissociated from the plasma membranes of the atrophied fibres. The atrophied fibres contained lysosomes and multivesicular bodies but their glycogen content was much reduced. By the 4th–6th week the fibres of soleus became restored to normal in size and abnormally abundant glycogen was then found. Fibres of gastrocnemius became more severely atrophied and showed many changes which were not seen in soleus fibres. These included focal disintegration of myofilaments, tubular aggregates, “helical complexes” and dilatation of cisternae. Recovery of gastrocnemius fibres began only after the 5th–6th week. In later stages there was splitting of muscle fibres in gastrocnemius and tubular aggregates, disoriented myofibrils forming annulets and centrally-located nuclei were common. Some fibres became considerably larger than normal but others showed extreme atrophy and disorganization of their internal structure many months after the injection of the toxin." @default.
- W2000319746 created "2016-06-24" @default.
- W2000319746 creator A5069313919 @default.
- W2000319746 date "1971-09-01" @default.
- W2000319746 modified "2023-10-13" @default.
- W2000319746 title "Changes in the electron microscopic structure of slow and fast skeletal muscle fibres of the mouse after the local injection of botulinum toxin" @default.
- W2000319746 cites W1982314081 @default.
- W2000319746 cites W1984993459 @default.
- W2000319746 cites W2017821757 @default.
- W2000319746 cites W2021419074 @default.
- W2000319746 cites W2026632766 @default.
- W2000319746 cites W2028875218 @default.
- W2000319746 cites W2068624139 @default.
- W2000319746 cites W2080197611 @default.
- W2000319746 cites W2083920741 @default.
- W2000319746 cites W2093716714 @default.
- W2000319746 cites W2124685534 @default.
- W2000319746 cites W2128987192 @default.
- W2000319746 doi "https://doi.org/10.1016/0022-510x(71)90130-4" @default.
- W2000319746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5119452" @default.
- W2000319746 hasPublicationYear "1971" @default.
- W2000319746 type Work @default.
- W2000319746 sameAs 2000319746 @default.
- W2000319746 citedByCount "78" @default.
- W2000319746 countsByYear W20003197462012 @default.
- W2000319746 countsByYear W20003197462013 @default.
- W2000319746 countsByYear W20003197462014 @default.
- W2000319746 countsByYear W20003197462015 @default.
- W2000319746 countsByYear W20003197462016 @default.
- W2000319746 countsByYear W20003197462017 @default.
- W2000319746 countsByYear W20003197462018 @default.
- W2000319746 countsByYear W20003197462021 @default.
- W2000319746 countsByYear W20003197462023 @default.
- W2000319746 crossrefType "journal-article" @default.
- W2000319746 hasAuthorship W2000319746A5069313919 @default.
- W2000319746 hasConcept C105702510 @default.
- W2000319746 hasConcept C12554922 @default.
- W2000319746 hasConcept C141071460 @default.
- W2000319746 hasConcept C142724271 @default.
- W2000319746 hasConcept C169760540 @default.
- W2000319746 hasConcept C174054327 @default.
- W2000319746 hasConcept C185592680 @default.
- W2000319746 hasConcept C27523624 @default.
- W2000319746 hasConcept C2775872116 @default.
- W2000319746 hasConcept C2776104385 @default.
- W2000319746 hasConcept C2776193487 @default.
- W2000319746 hasConcept C2777478456 @default.
- W2000319746 hasConcept C2777499176 @default.
- W2000319746 hasConcept C2779618896 @default.
- W2000319746 hasConcept C2779959927 @default.
- W2000319746 hasConcept C2781172350 @default.
- W2000319746 hasConcept C55493867 @default.
- W2000319746 hasConcept C6997183 @default.
- W2000319746 hasConcept C71924100 @default.
- W2000319746 hasConcept C7301908 @default.
- W2000319746 hasConcept C86803240 @default.
- W2000319746 hasConceptScore W2000319746C105702510 @default.
- W2000319746 hasConceptScore W2000319746C12554922 @default.
- W2000319746 hasConceptScore W2000319746C141071460 @default.
- W2000319746 hasConceptScore W2000319746C142724271 @default.
- W2000319746 hasConceptScore W2000319746C169760540 @default.
- W2000319746 hasConceptScore W2000319746C174054327 @default.
- W2000319746 hasConceptScore W2000319746C185592680 @default.
- W2000319746 hasConceptScore W2000319746C27523624 @default.
- W2000319746 hasConceptScore W2000319746C2775872116 @default.
- W2000319746 hasConceptScore W2000319746C2776104385 @default.
- W2000319746 hasConceptScore W2000319746C2776193487 @default.
- W2000319746 hasConceptScore W2000319746C2777478456 @default.
- W2000319746 hasConceptScore W2000319746C2777499176 @default.
- W2000319746 hasConceptScore W2000319746C2779618896 @default.
- W2000319746 hasConceptScore W2000319746C2779959927 @default.
- W2000319746 hasConceptScore W2000319746C2781172350 @default.
- W2000319746 hasConceptScore W2000319746C55493867 @default.
- W2000319746 hasConceptScore W2000319746C6997183 @default.
- W2000319746 hasConceptScore W2000319746C71924100 @default.
- W2000319746 hasConceptScore W2000319746C7301908 @default.
- W2000319746 hasConceptScore W2000319746C86803240 @default.
- W2000319746 hasIssue "1" @default.
- W2000319746 hasLocation W20003197461 @default.
- W2000319746 hasLocation W20003197462 @default.
- W2000319746 hasOpenAccess W2000319746 @default.
- W2000319746 hasPrimaryLocation W20003197461 @default.
- W2000319746 hasRelatedWork W1998404910 @default.
- W2000319746 hasRelatedWork W2002394114 @default.
- W2000319746 hasRelatedWork W2059114383 @default.
- W2000319746 hasRelatedWork W2060094016 @default.
- W2000319746 hasRelatedWork W2107233523 @default.
- W2000319746 hasRelatedWork W2108275102 @default.
- W2000319746 hasRelatedWork W2418315445 @default.
- W2000319746 hasRelatedWork W2437086105 @default.
- W2000319746 hasRelatedWork W247209062 @default.
- W2000319746 hasRelatedWork W4213441299 @default.
- W2000319746 hasVolume "14" @default.
- W2000319746 isParatext "false" @default.
- W2000319746 isRetracted "false" @default.
- W2000319746 magId "2000319746" @default.
- W2000319746 workType "article" @default.