FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000818307> ?p ?o ?g. }

• W2000818307 endingPage "8" @default.
• W2000818307 startingPage "1" @default.
• W2000818307 abstract "In obesity, the regulatory effects of leptin, a primarily adipocyte-derived hormone, are severely disturbed affecting the control of energy homeostasis and immune functions. In addition, recent studies indicate that specific immune cells can affect glucose and lipid metabolism of liver. However, the contribution of body weight and immune cells, such as Natural Killer (NK) cells, to the regulation of the leptin-receptor expression remains elusive. Therefore, we investigated the expression of the signal-transducing long form of the leptin receptor (Ob-Rb) in diet-induced obesity and after adoptive cross-over NK cell transfer between normal weight and obese male F344 rats. Expression of Ob-Rb was significantly increased in liver in diet-induced obese rats as compared to normal weight littermates. Similarly, the expression of Ob-Rb was higher in liver of obese animals that received NK cells from either obese or normal weight donors as compared to normal weight animals that received NK cells from normal weight donors. Interestingly, normal weight animals that were transferred with NK cells from obese donors also showed a tendency towards a higher Ob-Rb expression. In contrast to the findings in liver, the expression of Ob-Rb in spleen or lung remained unaffected by changes in body weight or cross-over NK cell transfer. Our results suggest that the expression of Ob-Rb mRNA in liver, but not in spleen or lung, is dependent on the body weight but can also be influenced by NK cells, thereby indicating a bidirectional cross-talk between the metabolic and the immune system." @default.
• W2000818307 created "2016-06-24" @default.
• W2000818307 creator A5009023308 @default.
• W2000818307 creator A5031035505 @default.
• W2000818307 creator A5051417620 @default.
• W2000818307 creator A5058266159 @default.
• W2000818307 creator A5084520603 @default.
• W2000818307 date "2010-01-01" @default.
• W2000818307 modified "2023-09-25" @default.
• W2000818307 title "Obesity and NK cells affect the expression of the long form of the leptin receptor Ob-Rb in liver of F344 rats" @default.
• W2000818307 cites W1567175289 @default.
• W2000818307 cites W1967451731 @default.
• W2000818307 cites W1970205234 @default.
• W2000818307 cites W1976560172 @default.
• W2000818307 cites W1988098212 @default.
• W2000818307 cites W1993088616 @default.
• W2000818307 cites W1996713062 @default.
• W2000818307 cites W2000054651 @default.
• W2000818307 cites W2012652877 @default.
• W2000818307 cites W2014163208 @default.
• W2000818307 cites W2022716990 @default.
• W2000818307 cites W2022975427 @default.
• W2000818307 cites W2028336115 @default.
• W2000818307 cites W2033204507 @default.
• W2000818307 cites W2041872947 @default.
• W2000818307 cites W2044153433 @default.
• W2000818307 cites W2053148847 @default.
• W2000818307 cites W2063674761 @default.
• W2000818307 cites W2066528365 @default.
• W2000818307 cites W2073300038 @default.
• W2000818307 cites W2075946858 @default.
• W2000818307 cites W2077724247 @default.
• W2000818307 cites W2088986234 @default.
• W2000818307 cites W2090701919 @default.
• W2000818307 cites W2092432949 @default.
• W2000818307 cites W2110743053 @default.
• W2000818307 cites W2132207275 @default.
• W2000818307 cites W2144568788 @default.
• W2000818307 cites W2161508215 @default.
• W2000818307 cites W2167485774 @default.
• W2000818307 cites W2171709048 @default.
• W2000818307 cites W2399733480 @default.
• W2000818307 cites W4255486898 @default.
• W2000818307 cites W4247198923 @default.
• W2000818307 doi "https://doi.org/10.1016/j.etp.2008.12.006" @default.
• W2000818307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19186040" @default.
• W2000818307 hasPublicationYear "2010" @default.
• W2000818307 type Work @default.
• W2000818307 sameAs 2000818307 @default.
• W2000818307 citedByCount "9" @default.
• W2000818307 countsByYear W20008183072012 @default.
• W2000818307 countsByYear W20008183072013 @default.
• W2000818307 countsByYear W20008183072014 @default.
• W2000818307 countsByYear W20008183072022 @default.
• W2000818307 crossrefType "journal-article" @default.
• W2000818307 hasAuthorship W2000818307A5009023308 @default.
• W2000818307 hasAuthorship W2000818307A5031035505 @default.
• W2000818307 hasAuthorship W2000818307A5051417620 @default.
• W2000818307 hasAuthorship W2000818307A5058266159 @default.
• W2000818307 hasAuthorship W2000818307A5084520603 @default.
• W2000818307 hasConcept C126322002 @default.
• W2000818307 hasConcept C134018914 @default.
• W2000818307 hasConcept C14372207 @default.
• W2000818307 hasConcept C170493617 @default.
• W2000818307 hasConcept C203014093 @default.
• W2000818307 hasConcept C2780613262 @default.
• W2000818307 hasConcept C2780931953 @default.
• W2000818307 hasConcept C511355011 @default.
• W2000818307 hasConcept C71924100 @default.
• W2000818307 hasConcept C86803240 @default.
• W2000818307 hasConcept C8891405 @default.
• W2000818307 hasConceptScore W2000818307C126322002 @default.
• W2000818307 hasConceptScore W2000818307C134018914 @default.
• W2000818307 hasConceptScore W2000818307C14372207 @default.
• W2000818307 hasConceptScore W2000818307C170493617 @default.
• W2000818307 hasConceptScore W2000818307C203014093 @default.
• W2000818307 hasConceptScore W2000818307C2780613262 @default.
• W2000818307 hasConceptScore W2000818307C2780931953 @default.
• W2000818307 hasConceptScore W2000818307C511355011 @default.
• W2000818307 hasConceptScore W2000818307C71924100 @default.
• W2000818307 hasConceptScore W2000818307C86803240 @default.
• W2000818307 hasConceptScore W2000818307C8891405 @default.
• W2000818307 hasIssue "1" @default.
• W2000818307 hasLocation W20008183071 @default.
• W2000818307 hasLocation W20008183072 @default.
• W2000818307 hasOpenAccess W2000818307 @default.
• W2000818307 hasPrimaryLocation W20008183071 @default.
• W2000818307 hasRelatedWork W1976946227 @default.
• W2000818307 hasRelatedWork W1986171586 @default.
• W2000818307 hasRelatedWork W1994686423 @default.
• W2000818307 hasRelatedWork W2022716990 @default.
• W2000818307 hasRelatedWork W2029944781 @default.
• W2000818307 hasRelatedWork W2082814078 @default.
• W2000818307 hasRelatedWork W2138466941 @default.
• W2000818307 hasRelatedWork W2148844770 @default.
• W2000818307 hasRelatedWork W2182343999 @default.
• W2000818307 hasRelatedWork W2416108475 @default.
• W2000818307 hasVolume "62" @default.

• next