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• W2001005057 abstract "To investigate whether an insulin sensitizer has any effect on amenorrhea and clinical and biochemical hyperandrogenism in Chinese women with polycystic ovarian syndrome (PCOS).Randomized controlled double-blind trial.A tertiary referral center, Hong Kong.Chinese women who fulfilled the Rotterdam criteria of PCOS (n = 70).Rosiglitazone 4 mg daily for the first month followed by 4 mg twice daily for 11 months.Menstrual status as well as clinical and biochemical hyperandrogenism.There is a significantly higher rate of regular menses among the treatment arm (16 [50.0%] of 32 vs 4 [11.8%] of 34) at 6 months and the improvement appeared to be sustained (10 [41.7%] of 24 vs 6 [20.0%] of 30) at 12 months. There was no change in the acne and hirsutism scores as well as serum T levels in both arms.We found a possible benefit in menstrual cyclicity but a lack of improvement in hyperandrogenism in our Chinese population.ChiCTR-TRC-09000670 (Chinese Clinical Trial Registry)." @default.
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• W2001005057 date "2011-08-01" @default.
• W2001005057 modified "2023-10-16" @default.
• W2001005057 title "The reproductive and metabolic effect of rosiglitazone on Chinese women with polycystic ovarian syndrome—a double-blind randomized placebo-controlled study" @default.
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• W2001005057 doi "https://doi.org/10.1016/j.fertnstert.2011.05.085" @default.
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