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- W2008292652 abstract "Anti-aging and depigmentation have both been an important subject of study for skin disease and the cosmetic industry. Caffeic acid (CA) has shown synergistically enhanced antioxidant activity when conjugated with amino acids. Hydroxamic acid (NHOH) is a well-known metal chelator, potentially having both tyrosinase inhibitory activity and free radical scavenging activity. We prepared caffeoyl-amino acidyl-hydroxamic acid (CA-Xaa-NHOH) and found that caffeoyl-prolyl-hydroxamic acid (CA-Pro-NHOH) contained excellent antioxidant activity and tyrosinase inhibitory activity by various bioassay systems. Also, CA-Pro-NHOH showed mild melanogenesis inhibitory activity in Mel-Ab cells." @default.
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- W2008292652 date "2011-09-01" @default.
- W2008292652 modified "2023-10-03" @default.
- W2008292652 title "Dual effects of caffeoyl-amino acidyl-hydroxamic acid as an antioxidant and depigmenting agent" @default.
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- W2008292652 doi "https://doi.org/10.1016/j.bmcl.2011.07.064" @default.
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