Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008477703> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2008477703 endingPage "306" @default.
- W2008477703 startingPage "301" @default.
- W2008477703 abstract "Abstract The chemical behaviour of cytidine 5′-monophospho- N -acetylneuraminic acid (CMP–Neu5Ac) under different conditions was studied. We found that the stability of this sugar nucleotide in water and cacodylate buffer was high and similar in both systems, although it was more stable in ethanol/water. Hydrolysis rates increased with temperature. 2-Deoxy-2,3-dehydro- N -acetylneuraminic acid (NeuAc2en) was formed in the first few minutes of the treatments. CMP–Neu5Ac was more stable in alkaline (pH 8 and 10) than in acidic (pH 3 and 5) conditions; its stability was very similar in neutral (water and ethanol/water) and alkaline conditions. The yield of Neu5Ac2en increased with pH and temperature. Additionally, CMP–Neu5Ac dissolved in the solvent system n -butanol/ n -propanol/0.1 N HCl (pH 1) was hydrolyzed very fast (98–99% after 1 min). Moreover, this sugar nucleotide dissolved in water or cacodylate buffer (pH 5.8) and when subjected to successive freezing and thawing cycles did not show any increase in the hydrolysis rate. Finally, no decomposition of N -acetylneuraminic acid (Neu5Ac) or Neu5Ac2en was observed under the above-mentioned conditions (pH, temperature, freeze–thaw cycles)." @default.
- W2008477703 created "2016-06-24" @default.
- W2008477703 creator A5066934416 @default.
- W2008477703 creator A5071381255 @default.
- W2008477703 creator A5072136053 @default.
- W2008477703 date "1999-07-01" @default.
- W2008477703 modified "2023-10-15" @default.
- W2008477703 title "Degradation of cytidine 5′-monophospho-N-acetylneuraminic acid under different conditions" @default.
- W2008477703 cites W102475103 @default.
- W2008477703 cites W1970532616 @default.
- W2008477703 cites W1972159132 @default.
- W2008477703 cites W2011920569 @default.
- W2008477703 cites W2038679704 @default.
- W2008477703 cites W2044154170 @default.
- W2008477703 cites W2056757665 @default.
- W2008477703 cites W2058392980 @default.
- W2008477703 cites W2071565903 @default.
- W2008477703 cites W2123089615 @default.
- W2008477703 cites W2324174683 @default.
- W2008477703 cites W982669008 @default.
- W2008477703 doi "https://doi.org/10.1016/s0305-0491(99)00076-0" @default.
- W2008477703 hasPublicationYear "1999" @default.
- W2008477703 type Work @default.
- W2008477703 sameAs 2008477703 @default.
- W2008477703 citedByCount "5" @default.
- W2008477703 countsByYear W20084777032016 @default.
- W2008477703 countsByYear W20084777032020 @default.
- W2008477703 countsByYear W20084777032022 @default.
- W2008477703 countsByYear W20084777032023 @default.
- W2008477703 crossrefType "journal-article" @default.
- W2008477703 hasAuthorship W2008477703A5066934416 @default.
- W2008477703 hasAuthorship W2008477703A5071381255 @default.
- W2008477703 hasAuthorship W2008477703A5072136053 @default.
- W2008477703 hasConcept C181199279 @default.
- W2008477703 hasConcept C185592680 @default.
- W2008477703 hasConcept C2778671442 @default.
- W2008477703 hasConcept C2779679103 @default.
- W2008477703 hasConcept C2780115458 @default.
- W2008477703 hasConcept C2781184954 @default.
- W2008477703 hasConcept C41008148 @default.
- W2008477703 hasConcept C55493867 @default.
- W2008477703 hasConcept C76155785 @default.
- W2008477703 hasConceptScore W2008477703C181199279 @default.
- W2008477703 hasConceptScore W2008477703C185592680 @default.
- W2008477703 hasConceptScore W2008477703C2778671442 @default.
- W2008477703 hasConceptScore W2008477703C2779679103 @default.
- W2008477703 hasConceptScore W2008477703C2780115458 @default.
- W2008477703 hasConceptScore W2008477703C2781184954 @default.
- W2008477703 hasConceptScore W2008477703C41008148 @default.
- W2008477703 hasConceptScore W2008477703C55493867 @default.
- W2008477703 hasConceptScore W2008477703C76155785 @default.
- W2008477703 hasIssue "3" @default.
- W2008477703 hasLocation W20084777031 @default.
- W2008477703 hasOpenAccess W2008477703 @default.
- W2008477703 hasPrimaryLocation W20084777031 @default.
- W2008477703 hasRelatedWork W1566893509 @default.
- W2008477703 hasRelatedWork W1987586155 @default.
- W2008477703 hasRelatedWork W1998843541 @default.
- W2008477703 hasRelatedWork W2040225728 @default.
- W2008477703 hasRelatedWork W2058269227 @default.
- W2008477703 hasRelatedWork W2105160466 @default.
- W2008477703 hasRelatedWork W2165460884 @default.
- W2008477703 hasRelatedWork W2343399448 @default.
- W2008477703 hasRelatedWork W2345641464 @default.
- W2008477703 hasRelatedWork W24898298 @default.
- W2008477703 hasVolume "123" @default.
- W2008477703 isParatext "false" @default.
- W2008477703 isRetracted "false" @default.
- W2008477703 magId "2008477703" @default.
- W2008477703 workType "article" @default.