FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012148269> ?p ?o ?g. }

• W2012148269 abstract "A small percentage of mature mares continue to exhibit estrous cyclicity during the non-breeding season which is of interest because of the importance of timing of the breeding season to the equine breeding industry. Previously, it was demonstrated that the continuation of estrous cycles was more likely to occur in mature than young mares. Additionally, an apparent association exists between elevated body fat and increased circulating concentrations of leptin, and the occurrence of estrous cycles during the non-breeding season. Two experiments were conducted to test the hypothesis that pharmacological manipulation of body fat and leptin by administration of the beta(2)-adrenergic receptor agonist clenbuterol, with and without continuous treatment with melatonin, would increase the proportion of mares entering anestrus or advance its timing. In Experiment 1, eight mature mares were administered clenbuterol (3.2 microg/kg) daily from October through January and six mares were untreated. In Experiment 2, eight mares were administered clenbuterol daily from June through December, eight mares were treated with continuous release melatonin implants, and seven mares were treated with both clenbuterol and melatonin. Melatonin treatment was included to confirm previous results that constant treatment with melatonin did not advance the timing of anestrus. In both studies, leptin concentrations (P<0.01, both experiments) and body fat percentage (P<0.01, Experiment 1; P<0.05, Experiment 2) declined in response to daily clenbuterol treatment. Unexpectedly, however, this decrease was attenuated in mares also treated with melatonin (P<0.05). Although treatment with clenbuterol was associated with a decline in body fat and circulating concentrations of leptin, the timing or proportion of mares exhibiting anestrus was not modified (P>0.05). The results demonstrate the manipulation of body condition via pharmacological intervention does not modify the mechanisms controlling seasonal anestrus in the mare." @default.
• W2012148269 created "2016-06-24" @default.
• W2012148269 creator A5078339072 @default.
• W2012148269 creator A5086867527 @default.
• W2012148269 date "2003-04-01" @default.
• W2012148269 modified "2023-10-18" @default.
• W2012148269 title "Effect of daily clenbuterol and exogenous melatonin treatment on body fat, serum leptin and the expression of seasonal anestrus in the mare" @default.
• W2012148269 cites W1580569338 @default.
• W2012148269 cites W1791831929 @default.
• W2012148269 cites W1971674050 @default.
• W2012148269 cites W1972970479 @default.
• W2012148269 cites W1984234666 @default.
• W2012148269 cites W2005649591 @default.
• W2012148269 cites W2009029113 @default.
• W2012148269 cites W2044125094 @default.
• W2012148269 cites W2052858436 @default.
• W2012148269 cites W2060682066 @default.
• W2012148269 cites W2063777187 @default.
• W2012148269 cites W2067392075 @default.
• W2012148269 cites W207197865 @default.
• W2012148269 cites W2087133453 @default.
• W2012148269 cites W2110596632 @default.
• W2012148269 cites W2116930589 @default.
• W2012148269 cites W2125510262 @default.
• W2012148269 cites W2139582916 @default.
• W2012148269 cites W2281844807 @default.
• W2012148269 cites W2334337188 @default.
• W2012148269 cites W2547271346 @default.
• W2012148269 cites W321465631 @default.
• W2012148269 cites W4245413966 @default.
• W2012148269 cites W6013967 @default.
• W2012148269 doi "https://doi.org/10.1016/s0378-4320(02)00246-4" @default.
• W2012148269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12586494" @default.
• W2012148269 hasPublicationYear "2003" @default.
• W2012148269 type Work @default.
• W2012148269 sameAs 2012148269 @default.
• W2012148269 citedByCount "20" @default.
• W2012148269 countsByYear W20121482692013 @default.
• W2012148269 countsByYear W20121482692014 @default.
• W2012148269 countsByYear W20121482692015 @default.
• W2012148269 countsByYear W20121482692022 @default.
• W2012148269 crossrefType "journal-article" @default.
• W2012148269 hasAuthorship W2012148269A5078339072 @default.
• W2012148269 hasAuthorship W2012148269A5086867527 @default.
• W2012148269 hasConcept C102874275 @default.
• W2012148269 hasConcept C126322002 @default.
• W2012148269 hasConcept C134018914 @default.
• W2012148269 hasConcept C140793950 @default.
• W2012148269 hasConcept C170493617 @default.
• W2012148269 hasConcept C18903297 @default.
• W2012148269 hasConcept C1998276 @default.
• W2012148269 hasConcept C2776327530 @default.
• W2012148269 hasConcept C2778182776 @default.
• W2012148269 hasConcept C2778938600 @default.
• W2012148269 hasConcept C2780613262 @default.
• W2012148269 hasConcept C511355011 @default.
• W2012148269 hasConcept C59659247 @default.
• W2012148269 hasConcept C71924100 @default.
• W2012148269 hasConcept C86803240 @default.
• W2012148269 hasConceptScore W2012148269C102874275 @default.
• W2012148269 hasConceptScore W2012148269C126322002 @default.
• W2012148269 hasConceptScore W2012148269C134018914 @default.
• W2012148269 hasConceptScore W2012148269C140793950 @default.
• W2012148269 hasConceptScore W2012148269C170493617 @default.
• W2012148269 hasConceptScore W2012148269C18903297 @default.
• W2012148269 hasConceptScore W2012148269C1998276 @default.
• W2012148269 hasConceptScore W2012148269C2776327530 @default.
• W2012148269 hasConceptScore W2012148269C2778182776 @default.
• W2012148269 hasConceptScore W2012148269C2778938600 @default.
• W2012148269 hasConceptScore W2012148269C2780613262 @default.
• W2012148269 hasConceptScore W2012148269C511355011 @default.
• W2012148269 hasConceptScore W2012148269C59659247 @default.
• W2012148269 hasConceptScore W2012148269C71924100 @default.
• W2012148269 hasConceptScore W2012148269C86803240 @default.
• W2012148269 hasLocation W20121482691 @default.
• W2012148269 hasLocation W20121482692 @default.
• W2012148269 hasOpenAccess W2012148269 @default.
• W2012148269 hasPrimaryLocation W20121482691 @default.
• W2012148269 hasRelatedWork W1965429608 @default.
• W2012148269 hasRelatedWork W1981495544 @default.
• W2012148269 hasRelatedWork W1985016775 @default.
• W2012148269 hasRelatedWork W2008001590 @default.
• W2012148269 hasRelatedWork W2012148269 @default.
• W2012148269 hasRelatedWork W2044815141 @default.
• W2012148269 hasRelatedWork W2045522208 @default.
• W2012148269 hasRelatedWork W2131682885 @default.
• W2012148269 hasRelatedWork W2149230912 @default.
• W2012148269 hasRelatedWork W2797587270 @default.
• W2012148269 isParatext "false" @default.
• W2012148269 isRetracted "false" @default.
• W2012148269 magId "2012148269" @default.
• W2012148269 workType "article" @default.