Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016307601> ?p ?o ?g. }
- W2016307601 endingPage "1444" @default.
- W2016307601 startingPage "1437" @default.
- W2016307601 abstract "Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a newly identified anti-apoptotic molecule. Our previous studies have demonstrated that CIAPIN1 is ubiquitously expressed in normal fetal and adult human tissues and confers multidrug resistance in gastric cancer cells, possibly by upregulating the expression of multidrug resistance gene 1 and multidrug resistance-related protein 1. However, fundamental biological functions of CIAPIN1 have not been elucidated. In this study, we first predicted the subcellular localization of CIAPIN1 with bioinformatic approaches and then characterized the intracellular localization of CIAPIN1 in both human and mouse cells by a combination of techniques including (a)immunohistochemistry and immunofluorescence, (b) His-tagged CIAPIN1 expression, and (c)subcellular fractionation and analysis of CIAPIN1 in the fractions by Western blotting. All methods produced consistent results; CIAPIN1 was localized in both the cytoplasm and the nucleus and was accumulated in the nucleolus. Bioinformatic prediction disclosed a putative nuclear localization signal and a putative nuclear export signal within both human and mouse CIAPIN1. These findings suggest that CIAPIN1 may undergo a cytoplasm-nucleus-nucleolus translocation." @default.
- W2016307601 created "2016-06-24" @default.
- W2016307601 creator A5013398382 @default.
- W2016307601 creator A5020943098 @default.
- W2016307601 creator A5042231008 @default.
- W2016307601 creator A5056755738 @default.
- W2016307601 creator A5071814939 @default.
- W2016307601 creator A5081368889 @default.
- W2016307601 date "2006-08-09" @default.
- W2016307601 modified "2023-09-27" @default.
- W2016307601 title "Subcellular Localization of CIAPIN1" @default.
- W2016307601 cites W1148066314 @default.
- W2016307601 cites W1491701783 @default.
- W2016307601 cites W1493968401 @default.
- W2016307601 cites W1627945794 @default.
- W2016307601 cites W1927581912 @default.
- W2016307601 cites W1966521400 @default.
- W2016307601 cites W1968375984 @default.
- W2016307601 cites W1973616414 @default.
- W2016307601 cites W1983110195 @default.
- W2016307601 cites W1985081377 @default.
- W2016307601 cites W1993522288 @default.
- W2016307601 cites W2006211612 @default.
- W2016307601 cites W2009565961 @default.
- W2016307601 cites W2011721592 @default.
- W2016307601 cites W2026123190 @default.
- W2016307601 cites W2026178507 @default.
- W2016307601 cites W2032640145 @default.
- W2016307601 cites W2042404454 @default.
- W2016307601 cites W2048653746 @default.
- W2016307601 cites W2053890772 @default.
- W2016307601 cites W2055099935 @default.
- W2016307601 cites W2061637725 @default.
- W2016307601 cites W2069908608 @default.
- W2016307601 cites W2071454543 @default.
- W2016307601 cites W2072674303 @default.
- W2016307601 cites W2073781325 @default.
- W2016307601 cites W2087642779 @default.
- W2016307601 cites W2094931538 @default.
- W2016307601 cites W2098507408 @default.
- W2016307601 cites W2101745615 @default.
- W2016307601 cites W2105661146 @default.
- W2016307601 cites W2106882534 @default.
- W2016307601 cites W2118961059 @default.
- W2016307601 cites W2120754979 @default.
- W2016307601 cites W2123657381 @default.
- W2016307601 cites W2130317021 @default.
- W2016307601 cites W2136930152 @default.
- W2016307601 cites W2143528844 @default.
- W2016307601 cites W2144781426 @default.
- W2016307601 cites W2152121872 @default.
- W2016307601 cites W2158125183 @default.
- W2016307601 cites W2160753380 @default.
- W2016307601 cites W2160979370 @default.
- W2016307601 cites W2167645623 @default.
- W2016307601 cites W2321142421 @default.
- W2016307601 cites W2617847000 @default.
- W2016307601 doi "https://doi.org/10.1369/jhc.6a6960.2006" @default.
- W2016307601 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3958118" @default.
- W2016307601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16957168" @default.
- W2016307601 hasPublicationYear "2006" @default.
- W2016307601 type Work @default.
- W2016307601 sameAs 2016307601 @default.
- W2016307601 citedByCount "26" @default.
- W2016307601 countsByYear W20163076012012 @default.
- W2016307601 countsByYear W20163076012013 @default.
- W2016307601 countsByYear W20163076012016 @default.
- W2016307601 countsByYear W20163076012019 @default.
- W2016307601 countsByYear W20163076012021 @default.
- W2016307601 countsByYear W20163076012022 @default.
- W2016307601 countsByYear W20163076012023 @default.
- W2016307601 crossrefType "journal-article" @default.
- W2016307601 hasAuthorship W2016307601A5013398382 @default.
- W2016307601 hasAuthorship W2016307601A5020943098 @default.
- W2016307601 hasAuthorship W2016307601A5042231008 @default.
- W2016307601 hasAuthorship W2016307601A5056755738 @default.
- W2016307601 hasAuthorship W2016307601A5071814939 @default.
- W2016307601 hasAuthorship W2016307601A5081368889 @default.
- W2016307601 hasBestOaLocation W20163076011 @default.
- W2016307601 hasConcept C104317684 @default.
- W2016307601 hasConcept C140051345 @default.
- W2016307601 hasConcept C153911025 @default.
- W2016307601 hasConcept C181199279 @default.
- W2016307601 hasConcept C183873130 @default.
- W2016307601 hasConcept C190062978 @default.
- W2016307601 hasConcept C27239569 @default.
- W2016307601 hasConcept C2776879804 @default.
- W2016307601 hasConcept C2780114586 @default.
- W2016307601 hasConcept C2780723820 @default.
- W2016307601 hasConcept C49805395 @default.
- W2016307601 hasConcept C55493867 @default.
- W2016307601 hasConcept C85265743 @default.
- W2016307601 hasConcept C86803240 @default.
- W2016307601 hasConcept C95444343 @default.
- W2016307601 hasConceptScore W2016307601C104317684 @default.
- W2016307601 hasConceptScore W2016307601C140051345 @default.
- W2016307601 hasConceptScore W2016307601C153911025 @default.
- W2016307601 hasConceptScore W2016307601C181199279 @default.