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- W2017566747 abstract "Taurospongin A (1), a novel acetylene-containing natural product consisting of a taurine and two fatty acid residues, has been isolated from the Okinawan marine sponge Hippospongia sp. and its structure elucidated by spectral data and chemical means. Taurospongin A (1) exhibited potent inhibitory activity against DNA polymerase β and HIV reverse transcriptase. The absolute configurations of taurospongin A (1) were established to be 3R, 7S, and 9R by synthesis of the MTPA ester of a degradation product of 1." @default.
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- W2017566747 date "2010-08-03" @default.
- W2017566747 modified "2023-10-10" @default.
- W2017566747 title "ChemInform Abstract: Taurospongin A, a Novel Acetylenic Fatty Acid Derivative Inhibiting DNA Polymerase β and HIV Reverse Transcriptase from Sponge Hippospongia sp." @default.
- W2017566747 cites W2949412106 @default.
- W2017566747 doi "https://doi.org/10.1002/chin.199742273" @default.
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