Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021008733> ?p ?o ?g. }
- W2021008733 endingPage "145" @default.
- W2021008733 startingPage "139" @default.
- W2021008733 abstract "Specific colonization of solid tumors by bacteria opens the way to novel approaches in both tumor diagnosis and therapy. However, even non-pathogenic bacteria induce responses by the immune system, which could be devastating for a tumor bearing patient. As such effects are caused e.g. by the lipid A moiety of the lipopolysaccharide, a msbB-mutant of the probiotic E. coli Nissle 1917 strain was investigated. Bacteria of the mutant strain did not show any growth defects in culture media when compared to wild-type E. coli Nissle 1917 but were unable to myristoylate lipid A, had less toxic effects on immunocompetent BALB/c mice, and were still able to specifically colonize tumors. Therefore, the modification of lipid A could result in bacterial strains that might be better suited for diagnosis and therapy of tumors than the corresponding wild-type strains, even if those are not considered pathogenic or are of probiotic background." @default.
- W2021008733 created "2016-06-24" @default.
- W2021008733 creator A5006952655 @default.
- W2021008733 creator A5027896478 @default.
- W2021008733 creator A5030665080 @default.
- W2021008733 creator A5051659038 @default.
- W2021008733 date "2010-03-01" @default.
- W2021008733 modified "2023-10-14" @default.
- W2021008733 title "Myristoylation negative msbB-mutants of probiotic E. coli Nissle 1917 retain tumor specific colonization properties but show less side effects in immunocompetent mice" @default.
- W2021008733 cites W1536714132 @default.
- W2021008733 cites W1542029261 @default.
- W2021008733 cites W1580197135 @default.
- W2021008733 cites W1595241211 @default.
- W2021008733 cites W186023911 @default.
- W2021008733 cites W1930598094 @default.
- W2021008733 cites W1936399524 @default.
- W2021008733 cites W1964822107 @default.
- W2021008733 cites W1973123246 @default.
- W2021008733 cites W1975515428 @default.
- W2021008733 cites W1990076541 @default.
- W2021008733 cites W2006697711 @default.
- W2021008733 cites W2008184405 @default.
- W2021008733 cites W2011403272 @default.
- W2021008733 cites W2012873467 @default.
- W2021008733 cites W2016136239 @default.
- W2021008733 cites W2018683219 @default.
- W2021008733 cites W2023429099 @default.
- W2021008733 cites W2023594725 @default.
- W2021008733 cites W2032515207 @default.
- W2021008733 cites W2065186465 @default.
- W2021008733 cites W2069655066 @default.
- W2021008733 cites W2077530057 @default.
- W2021008733 cites W2099399224 @default.
- W2021008733 cites W2109439790 @default.
- W2021008733 cites W2111389902 @default.
- W2021008733 cites W2115205513 @default.
- W2021008733 cites W2117986752 @default.
- W2021008733 cites W2135224891 @default.
- W2021008733 cites W2136246490 @default.
- W2021008733 cites W2136723682 @default.
- W2021008733 cites W2139971026 @default.
- W2021008733 cites W2144220448 @default.
- W2021008733 cites W2146948320 @default.
- W2021008733 cites W2147729711 @default.
- W2021008733 cites W2149116091 @default.
- W2021008733 cites W2150565980 @default.
- W2021008733 cites W2155793921 @default.
- W2021008733 cites W2160133892 @default.
- W2021008733 cites W2162428378 @default.
- W2021008733 cites W2167807283 @default.
- W2021008733 cites W2409599919 @default.
- W2021008733 cites W4234317413 @default.
- W2021008733 cites W4239206281 @default.
- W2021008733 cites W92958171 @default.
- W2021008733 doi "https://doi.org/10.4161/bbug.1.2.10286" @default.
- W2021008733 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3026454" @default.
- W2021008733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21326939" @default.
- W2021008733 hasPublicationYear "2010" @default.
- W2021008733 type Work @default.
- W2021008733 sameAs 2021008733 @default.
- W2021008733 citedByCount "9" @default.
- W2021008733 countsByYear W20210087332012 @default.
- W2021008733 countsByYear W20210087332016 @default.
- W2021008733 countsByYear W20210087332018 @default.
- W2021008733 countsByYear W20210087332021 @default.
- W2021008733 countsByYear W20210087332022 @default.
- W2021008733 crossrefType "journal-article" @default.
- W2021008733 hasAuthorship W2021008733A5006952655 @default.
- W2021008733 hasAuthorship W2021008733A5027896478 @default.
- W2021008733 hasAuthorship W2021008733A5030665080 @default.
- W2021008733 hasAuthorship W2021008733A5051659038 @default.
- W2021008733 hasBestOaLocation W20210087331 @default.
- W2021008733 hasConcept C104317684 @default.
- W2021008733 hasConcept C105702510 @default.
- W2021008733 hasConcept C143065580 @default.
- W2021008733 hasConcept C144464004 @default.
- W2021008733 hasConcept C203014093 @default.
- W2021008733 hasConcept C2778022156 @default.
- W2021008733 hasConcept C2778754761 @default.
- W2021008733 hasConcept C2778883795 @default.
- W2021008733 hasConcept C2780255968 @default.
- W2021008733 hasConcept C523546767 @default.
- W2021008733 hasConcept C54355233 @default.
- W2021008733 hasConcept C547475151 @default.
- W2021008733 hasConcept C55493867 @default.
- W2021008733 hasConcept C86803240 @default.
- W2021008733 hasConcept C8891405 @default.
- W2021008733 hasConcept C89423630 @default.
- W2021008733 hasConceptScore W2021008733C104317684 @default.
- W2021008733 hasConceptScore W2021008733C105702510 @default.
- W2021008733 hasConceptScore W2021008733C143065580 @default.
- W2021008733 hasConceptScore W2021008733C144464004 @default.
- W2021008733 hasConceptScore W2021008733C203014093 @default.
- W2021008733 hasConceptScore W2021008733C2778022156 @default.
- W2021008733 hasConceptScore W2021008733C2778754761 @default.
- W2021008733 hasConceptScore W2021008733C2778883795 @default.
- W2021008733 hasConceptScore W2021008733C2780255968 @default.
- W2021008733 hasConceptScore W2021008733C523546767 @default.