Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021503215> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2021503215 endingPage "506" @default.
- W2021503215 startingPage "500" @default.
- W2021503215 abstract "The human Xp22.3-p22.2 region contains several known disease genes as well as distinctive families of low copy repetitive sequences. In this study, we have developed new tools to more finely map this area. We bare characterized a mapping panel of various cell lines and hybrids with different molecular breakpoints as defined by previously mapped reference markers from this region. The panel subdivides this area into nine distinct regions from DXS41 through the pseudoautosomal boundary. We have also identified a radiation-reduced somatic cell hybrid, Z4-7, that contains DXS31, DXS452, STS, DXS143, and DXS85, but not PABX, DXS16, or other single-copy probes from proximal Xp and Xq. A phage library was constructed from Z4-7 and over 80,000 plaques were screened with total human DNA. More than 100 positive clones were identified as potential new markers in this region. Nine of these have been mapped to the hybrid panel, and unique subclones have been isolated from three of these markers. The panel has also allowed us to map several other DNA markers, genes (AMG, OA1), and repetitive elements of the DXF22S and DXF30S sequence families relative to the various breakpoints." @default.
- W2021503215 created "2016-06-24" @default.
- W2021503215 creator A5023326204 @default.
- W2021503215 creator A5028069586 @default.
- W2021503215 creator A5044887457 @default.
- W2021503215 creator A5048302189 @default.
- W2021503215 creator A5051040365 @default.
- W2021503215 date "1993-03-01" @default.
- W2021503215 modified "2023-10-12" @default.
- W2021503215 title "Deletion Mapping and a Highly Reduced Radiation Hybrid in the Xp22.3-p22.2 Region" @default.
- W2021503215 doi "https://doi.org/10.1006/geno.1993.1100" @default.
- W2021503215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8468044" @default.
- W2021503215 hasPublicationYear "1993" @default.
- W2021503215 type Work @default.
- W2021503215 sameAs 2021503215 @default.
- W2021503215 citedByCount "6" @default.
- W2021503215 crossrefType "journal-article" @default.
- W2021503215 hasAuthorship W2021503215A5023326204 @default.
- W2021503215 hasAuthorship W2021503215A5028069586 @default.
- W2021503215 hasAuthorship W2021503215A5044887457 @default.
- W2021503215 hasAuthorship W2021503215A5048302189 @default.
- W2021503215 hasAuthorship W2021503215A5051040365 @default.
- W2021503215 hasBestOaLocation W20215032151 @default.
- W2021503215 hasConcept C104317684 @default.
- W2021503215 hasConcept C122735190 @default.
- W2021503215 hasConcept C153911025 @default.
- W2021503215 hasConcept C169836425 @default.
- W2021503215 hasConcept C206625514 @default.
- W2021503215 hasConcept C206936463 @default.
- W2021503215 hasConcept C2777714445 @default.
- W2021503215 hasConcept C30481170 @default.
- W2021503215 hasConcept C35158069 @default.
- W2021503215 hasConcept C54355233 @default.
- W2021503215 hasConcept C86803240 @default.
- W2021503215 hasConceptScore W2021503215C104317684 @default.
- W2021503215 hasConceptScore W2021503215C122735190 @default.
- W2021503215 hasConceptScore W2021503215C153911025 @default.
- W2021503215 hasConceptScore W2021503215C169836425 @default.
- W2021503215 hasConceptScore W2021503215C206625514 @default.
- W2021503215 hasConceptScore W2021503215C206936463 @default.
- W2021503215 hasConceptScore W2021503215C2777714445 @default.
- W2021503215 hasConceptScore W2021503215C30481170 @default.
- W2021503215 hasConceptScore W2021503215C35158069 @default.
- W2021503215 hasConceptScore W2021503215C54355233 @default.
- W2021503215 hasConceptScore W2021503215C86803240 @default.
- W2021503215 hasIssue "3" @default.
- W2021503215 hasLocation W20215032151 @default.
- W2021503215 hasLocation W20215032152 @default.
- W2021503215 hasOpenAccess W2021503215 @default.
- W2021503215 hasPrimaryLocation W20215032151 @default.
- W2021503215 hasRelatedWork W2010896265 @default.
- W2021503215 hasRelatedWork W2011883498 @default.
- W2021503215 hasRelatedWork W2088671134 @default.
- W2021503215 hasRelatedWork W2089321487 @default.
- W2021503215 hasRelatedWork W2170550147 @default.
- W2021503215 hasRelatedWork W2171567466 @default.
- W2021503215 hasRelatedWork W2215305983 @default.
- W2021503215 hasRelatedWork W2308736777 @default.
- W2021503215 hasRelatedWork W2950656795 @default.
- W2021503215 hasRelatedWork W3028178966 @default.
- W2021503215 hasVolume "15" @default.
- W2021503215 isParatext "false" @default.
- W2021503215 isRetracted "false" @default.
- W2021503215 magId "2021503215" @default.
- W2021503215 workType "article" @default.