Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022796193> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2022796193 endingPage "1414" @default.
- W2022796193 startingPage "1414" @default.
- W2022796193 abstract "Deficient opsonization of yeasts, assessed by a microscopic method, has been reported as a frequent occurrence in children with recurrent infections (Soothill & Harvey, Arch. Dis. Childh. 51: 91, 1976) and in atopic patients (Turner et al.Clin. exp.Immunol.34: 253, 1978).We have studied opsonization spectrophotometrically by the stimulation, induced by serum, of the reduction of nitrobluetetrazolium which accompanies the phagocytosis of zymosan by PMN leucocytes. In 44 normal adults, half-maximal stimulation (S 0.5) was observed with a serum concentration of 3.1% ± 0.6 (mean ± St. dev.) Opsonization was considered deficient when S 0.5 was increased above 4.3% (+ 2 st.dev.).In accordance with Soothill et al., defective opsonization was occasionally found in healthy adults (3/47). Opsonization was studied in 91 children divided in 4 groups. In 22 children with various non-infectious diseases, including 6 with eczema, opsonization was normal. Deficient opsonization was found in 4 ( 14.3%,n.s.) out of 28 children hospitalized for a single acute infection, in 9 (50%, X2=13.7,p < 0.001) out of 18 children with a history of 3 or more severe infections (pneumonia, meningitis, sepsis) and in 2 (8.7%,n.s.)out of 23 children with frequent more benign infections (otitis, bronchitis). These results confirm the association of defective opsonization with an increased susceptibility to severe recurrent infections." @default.
- W2022796193 created "2016-06-24" @default.
- W2022796193 creator A5012319900 @default.
- W2022796193 creator A5047905695 @default.
- W2022796193 creator A5052017548 @default.
- W2022796193 creator A5066275742 @default.
- W2022796193 date "1980-12-01" @default.
- W2022796193 modified "2023-10-18" @default.
- W2022796193 title "DEFECTIVE OPSONIZATION IN RECURRENT INFECTIONS" @default.
- W2022796193 doi "https://doi.org/10.1203/00006450-198012000-00035" @default.
- W2022796193 hasPublicationYear "1980" @default.
- W2022796193 type Work @default.
- W2022796193 sameAs 2022796193 @default.
- W2022796193 citedByCount "0" @default.
- W2022796193 crossrefType "journal-article" @default.
- W2022796193 hasAuthorship W2022796193A5012319900 @default.
- W2022796193 hasAuthorship W2022796193A5047905695 @default.
- W2022796193 hasAuthorship W2022796193A5052017548 @default.
- W2022796193 hasAuthorship W2022796193A5066275742 @default.
- W2022796193 hasBestOaLocation W20227961931 @default.
- W2022796193 hasConcept C126322002 @default.
- W2022796193 hasConcept C160448771 @default.
- W2022796193 hasConcept C168507396 @default.
- W2022796193 hasConcept C203014093 @default.
- W2022796193 hasConcept C2777628635 @default.
- W2022796193 hasConcept C2777914695 @default.
- W2022796193 hasConcept C2778384902 @default.
- W2022796193 hasConcept C71924100 @default.
- W2022796193 hasConcept C89372155 @default.
- W2022796193 hasConceptScore W2022796193C126322002 @default.
- W2022796193 hasConceptScore W2022796193C160448771 @default.
- W2022796193 hasConceptScore W2022796193C168507396 @default.
- W2022796193 hasConceptScore W2022796193C203014093 @default.
- W2022796193 hasConceptScore W2022796193C2777628635 @default.
- W2022796193 hasConceptScore W2022796193C2777914695 @default.
- W2022796193 hasConceptScore W2022796193C2778384902 @default.
- W2022796193 hasConceptScore W2022796193C71924100 @default.
- W2022796193 hasConceptScore W2022796193C89372155 @default.
- W2022796193 hasIssue "12" @default.
- W2022796193 hasLocation W20227961931 @default.
- W2022796193 hasOpenAccess W2022796193 @default.
- W2022796193 hasPrimaryLocation W20227961931 @default.
- W2022796193 hasRelatedWork W139614779 @default.
- W2022796193 hasRelatedWork W1992803580 @default.
- W2022796193 hasRelatedWork W2026310579 @default.
- W2022796193 hasRelatedWork W2089103641 @default.
- W2022796193 hasRelatedWork W2108039615 @default.
- W2022796193 hasRelatedWork W2409960533 @default.
- W2022796193 hasRelatedWork W2619332145 @default.
- W2022796193 hasRelatedWork W2893007486 @default.
- W2022796193 hasRelatedWork W2998412934 @default.
- W2022796193 hasRelatedWork W3031257804 @default.
- W2022796193 hasVolume "14" @default.
- W2022796193 isParatext "false" @default.
- W2022796193 isRetracted "false" @default.
- W2022796193 magId "2022796193" @default.
- W2022796193 workType "article" @default.