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- W2025255744 abstract "In 2011, the European Commission has restricted the use of Bisphenol A in plastic infant feeding bottles. In a response to this restriction, Bisphenol S is now often used as a component of plastic substitutes for the production of babybottles. One of the major concerns leading to the restriction of Bisphenol A was its weak estrogenic activity. By using two highly standardised transactivation assays, we could demonstrate that the estrogenic activity of Bisphenol A and Bisphenol S is of a comparable potency. Furthermore, some insights about the structure-activity relationships of these two chemicals and their metabolites could be gained from in silico predictions of their relative estrogen receptor-binding affinities and their liver phase-I biotransformation." @default.
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- W2025255744 date "2012-08-01" @default.
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- W2025255744 title "Weak estrogenic transcriptional activities of Bisphenol A and Bisphenol S" @default.
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- W2025255744 doi "https://doi.org/10.1016/j.tiv.2012.03.013" @default.
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