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- W2028353045 abstract "1,3-Di-ortho-tolylguanidine (DTG), a compound with marked selectivity for σ receptors was iontophoretically applied to neurons in the red nucleus and nearby mesencephalic reticular formation. Spontaneous firing of rubral neurons was reduced by DTG in most cases. However, in the reticular formation, less than half of the cells tested showed inhinition; the remaining cells showed either an increase in rate or no consistent response to DTG. This corresponds to the greater density of σ receptors in the red nucleus and supports previous work which suggests that σ receptors play a role in the regulation of movement and posture." @default.
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- W2028353045 date "1988-12-01" @default.
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- W2028353045 title "Inhibition of rubral neurons by a specific ligand for σ receptors" @default.
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- W2028353045 doi "https://doi.org/10.1016/0014-2999(88)90268-3" @default.
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