FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033024369> ?p ?o ?g. }

• W2033024369 endingPage "113" @default.
• W2033024369 startingPage "107" @default.
• W2033024369 abstract "At present, the analytical method for paralytic shellfish poisoning (PSP) toxins in shellfish is the mouse bioassay (MBA), which is an official method of the Association of Analytical Communities (AOAC [8]). However, the low sensitivity and concerns over the number of live animals required for testing have been cited as the major reason for seeking its replacement. In this report, we employed an open-sandwich immunoassay (OS-IA) to detect gonyautoxin (GTX2/3), a kind of PSP toxins. OS-IA, which utilizes the antigen-induced enhancement of antibody VH/VL interaction, can measure a small molecule antigen in a noncompetitive format. Hence it has a wider working range and shorter measurement time. We isolated anti-GTX2/3 antibody gene from a hybridoma GT-13A by screening a Fab-displaying phage library. Then the vectors for OS-IA were constructed, and examined for antigen concentration-dependency of the VH/VL interaction by OS-ELISA. As a result, in each case, signal intensity increases notably in a wide concentration range (0.1 to >1000 ng mL−1) of free GTX2/3, which was enough to cover its regulation value (80 μg 100 g−1) in many countries. So OS-IA will be widely applicable to detect PSP toxins in shellfish meats and in drinking water." @default.
• W2033024369 created "2016-06-24" @default.
• W2033024369 creator A5008734520 @default.
• W2033024369 creator A5044773604 @default.
• W2033024369 creator A5069612108 @default.
• W2033024369 date "2013-09-01" @default.
• W2033024369 modified "2023-09-30" @default.
• W2033024369 title "Open-sandwich immunoassay for sensitive and broad-range detection of a shellfish toxin gonyautoxin" @default.
• W2033024369 cites W1967720466 @default.
• W2033024369 cites W1972471260 @default.
• W2033024369 cites W1978134503 @default.
• W2033024369 cites W1992314247 @default.
• W2033024369 cites W1995023400 @default.
• W2033024369 cites W2013293263 @default.
• W2033024369 cites W2015132974 @default.
• W2033024369 cites W2028259150 @default.
• W2033024369 cites W2028922575 @default.
• W2033024369 cites W2035250598 @default.
• W2033024369 cites W2041651570 @default.
• W2033024369 cites W2045184706 @default.
• W2033024369 cites W2049018948 @default.
• W2033024369 cites W2056970462 @default.
• W2033024369 cites W2058031874 @default.
• W2033024369 cites W2068203262 @default.
• W2033024369 cites W2071135488 @default.
• W2033024369 cites W2075690506 @default.
• W2033024369 cites W2080959815 @default.
• W2033024369 cites W2085025732 @default.
• W2033024369 cites W2087828028 @default.
• W2033024369 cites W2138188700 @default.
• W2033024369 cites W2312808237 @default.
• W2033024369 cites W2315289905 @default.
• W2033024369 cites W2465432198 @default.
• W2033024369 doi "https://doi.org/10.1016/j.aca.2013.07.024" @default.
• W2033024369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23953213" @default.
• W2033024369 hasPublicationYear "2013" @default.
• W2033024369 type Work @default.
• W2033024369 sameAs 2033024369 @default.
• W2033024369 citedByCount "25" @default.
• W2033024369 countsByYear W20330243692014 @default.
• W2033024369 countsByYear W20330243692015 @default.
• W2033024369 countsByYear W20330243692016 @default.
• W2033024369 countsByYear W20330243692017 @default.
• W2033024369 countsByYear W20330243692018 @default.
• W2033024369 countsByYear W20330243692021 @default.
• W2033024369 countsByYear W20330243692022 @default.
• W2033024369 countsByYear W20330243692023 @default.
• W2033024369 crossrefType "journal-article" @default.
• W2033024369 hasAuthorship W2033024369A5008734520 @default.
• W2033024369 hasAuthorship W2033024369A5044773604 @default.
• W2033024369 hasAuthorship W2033024369A5069612108 @default.
• W2033024369 hasConcept C119128265 @default.
• W2033024369 hasConcept C14086860 @default.
• W2033024369 hasConcept C147483822 @default.
• W2033024369 hasConcept C158278297 @default.
• W2033024369 hasConcept C159654299 @default.
• W2033024369 hasConcept C185592680 @default.
• W2033024369 hasConcept C186268636 @default.
• W2033024369 hasConcept C203014093 @default.
• W2033024369 hasConcept C2777367657 @default.
• W2033024369 hasConcept C2779281246 @default.
• W2033024369 hasConcept C2779792404 @default.
• W2033024369 hasConcept C2780420688 @default.
• W2033024369 hasConcept C2781028344 @default.
• W2033024369 hasConcept C2909208804 @default.
• W2033024369 hasConcept C43617362 @default.
• W2033024369 hasConcept C505870484 @default.
• W2033024369 hasConcept C55493867 @default.
• W2033024369 hasConcept C86803240 @default.
• W2033024369 hasConceptScore W2033024369C119128265 @default.
• W2033024369 hasConceptScore W2033024369C14086860 @default.
• W2033024369 hasConceptScore W2033024369C147483822 @default.
• W2033024369 hasConceptScore W2033024369C158278297 @default.
• W2033024369 hasConceptScore W2033024369C159654299 @default.
• W2033024369 hasConceptScore W2033024369C185592680 @default.
• W2033024369 hasConceptScore W2033024369C186268636 @default.
• W2033024369 hasConceptScore W2033024369C203014093 @default.
• W2033024369 hasConceptScore W2033024369C2777367657 @default.
• W2033024369 hasConceptScore W2033024369C2779281246 @default.
• W2033024369 hasConceptScore W2033024369C2779792404 @default.
• W2033024369 hasConceptScore W2033024369C2780420688 @default.
• W2033024369 hasConceptScore W2033024369C2781028344 @default.
• W2033024369 hasConceptScore W2033024369C2909208804 @default.
• W2033024369 hasConceptScore W2033024369C43617362 @default.
• W2033024369 hasConceptScore W2033024369C505870484 @default.
• W2033024369 hasConceptScore W2033024369C55493867 @default.
• W2033024369 hasConceptScore W2033024369C86803240 @default.
• W2033024369 hasFunder F4320320912 @default.
• W2033024369 hasLocation W20330243691 @default.
• W2033024369 hasLocation W20330243692 @default.
• W2033024369 hasOpenAccess W2033024369 @default.
• W2033024369 hasPrimaryLocation W20330243691 @default.
• W2033024369 hasRelatedWork W1992927125 @default.
• W2033024369 hasRelatedWork W2012373677 @default.
• W2033024369 hasRelatedWork W2033024369 @default.
• W2033024369 hasRelatedWork W2074819373 @default.
• W2033024369 hasRelatedWork W2132704369 @default.
• W2033024369 hasRelatedWork W2403968289 @default.

• next