Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035077457> ?p ?o ?g. }
- W2035077457 endingPage "12870" @default.
- W2035077457 startingPage "12860" @default.
- W2035077457 abstract "Cyclic diguanylate (c-di-GMP) is an allosteric activator and second messenger implicated in the regulation of a variety of biological processes in diverse bacteria. In Vibrio cholerae, c-di-GMP has been shown to inversely regulate biofilm-specific and virulence gene expression, suggesting that c-di-GMP signaling is important for the transition of V. cholerae from the environment to the host. However, the mechanism behind this regulation remains unknown. Recently, it was proposed that the PilZ protein domain represents a c-di-GMP-binding domain. Here we show that V. cholerae PilZ proteins bind c-di-GMP specifically and are involved in the regulation of biofilm formation, motility, and virulence. These findings confirm a role for PilZ proteins as c-di-GMP-sensing proteins within the c-di-GMP signaling network." @default.
- W2035077457 created "2016-06-24" @default.
- W2035077457 creator A5004538106 @default.
- W2035077457 creator A5009524336 @default.
- W2035077457 creator A5073663741 @default.
- W2035077457 creator A5084941155 @default.
- W2035077457 date "2007-04-01" @default.
- W2035077457 modified "2023-10-11" @default.
- W2035077457 title "PilZ Domain Proteins Bind Cyclic Diguanylate and Regulate Diverse Processes in Vibrio cholerae" @default.
- W2035077457 cites W1501582616 @default.
- W2035077457 cites W1543032176 @default.
- W2035077457 cites W1550927566 @default.
- W2035077457 cites W1598064331 @default.
- W2035077457 cites W1787690277 @default.
- W2035077457 cites W1886214354 @default.
- W2035077457 cites W1931700765 @default.
- W2035077457 cites W1944284471 @default.
- W2035077457 cites W1963147033 @default.
- W2035077457 cites W1970057259 @default.
- W2035077457 cites W1976347829 @default.
- W2035077457 cites W1977906605 @default.
- W2035077457 cites W1988051639 @default.
- W2035077457 cites W1990657825 @default.
- W2035077457 cites W1991373417 @default.
- W2035077457 cites W2000685678 @default.
- W2035077457 cites W2001035552 @default.
- W2035077457 cites W2003343094 @default.
- W2035077457 cites W2016814816 @default.
- W2035077457 cites W2030929667 @default.
- W2035077457 cites W2041355006 @default.
- W2035077457 cites W2052105084 @default.
- W2035077457 cites W2059032411 @default.
- W2035077457 cites W2061036236 @default.
- W2035077457 cites W2061670564 @default.
- W2035077457 cites W2083528938 @default.
- W2035077457 cites W2086341268 @default.
- W2035077457 cites W2087017025 @default.
- W2035077457 cites W2095209497 @default.
- W2035077457 cites W2096997859 @default.
- W2035077457 cites W2102239053 @default.
- W2035077457 cites W2106923147 @default.
- W2035077457 cites W2109216140 @default.
- W2035077457 cites W2117664645 @default.
- W2035077457 cites W2118242179 @default.
- W2035077457 cites W2121803750 @default.
- W2035077457 cites W2128355570 @default.
- W2035077457 cites W2132417094 @default.
- W2035077457 cites W2137871890 @default.
- W2035077457 cites W2143402559 @default.
- W2035077457 cites W2145131996 @default.
- W2035077457 cites W2145635847 @default.
- W2035077457 cites W2145792008 @default.
- W2035077457 cites W2146429915 @default.
- W2035077457 cites W2147185759 @default.
- W2035077457 cites W2148915230 @default.
- W2035077457 cites W2152817710 @default.
- W2035077457 cites W2156062569 @default.
- W2035077457 cites W2160084442 @default.
- W2035077457 cites W2160765784 @default.
- W2035077457 cites W2164263567 @default.
- W2035077457 cites W2165490685 @default.
- W2035077457 cites W2169054644 @default.
- W2035077457 cites W2171261016 @default.
- W2035077457 cites W2290245223 @default.
- W2035077457 cites W4210400672 @default.
- W2035077457 doi "https://doi.org/10.1074/jbc.m611593200" @default.
- W2035077457 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2790426" @default.
- W2035077457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17307739" @default.
- W2035077457 hasPublicationYear "2007" @default.
- W2035077457 type Work @default.
- W2035077457 sameAs 2035077457 @default.
- W2035077457 citedByCount "175" @default.
- W2035077457 countsByYear W20350774572012 @default.
- W2035077457 countsByYear W20350774572013 @default.
- W2035077457 countsByYear W20350774572014 @default.
- W2035077457 countsByYear W20350774572015 @default.
- W2035077457 countsByYear W20350774572016 @default.
- W2035077457 countsByYear W20350774572017 @default.
- W2035077457 countsByYear W20350774572018 @default.
- W2035077457 countsByYear W20350774572019 @default.
- W2035077457 countsByYear W20350774572020 @default.
- W2035077457 countsByYear W20350774572021 @default.
- W2035077457 countsByYear W20350774572022 @default.
- W2035077457 countsByYear W20350774572023 @default.
- W2035077457 crossrefType "journal-article" @default.
- W2035077457 hasAuthorship W2035077457A5004538106 @default.
- W2035077457 hasAuthorship W2035077457A5009524336 @default.
- W2035077457 hasAuthorship W2035077457A5073663741 @default.
- W2035077457 hasAuthorship W2035077457A5084941155 @default.
- W2035077457 hasBestOaLocation W20350774571 @default.
- W2035077457 hasConcept C104317684 @default.
- W2035077457 hasConcept C163235415 @default.
- W2035077457 hasConcept C166342909 @default.
- W2035077457 hasConcept C170493617 @default.
- W2035077457 hasConcept C2778643871 @default.
- W2035077457 hasConcept C523546767 @default.
- W2035077457 hasConcept C54355233 @default.
- W2035077457 hasConcept C55493867 @default.