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- W2037081359 abstract "Chitosan/hydroxyapatite composite rods are good candidates as temporary mechanical supports in bone regeneration; however the mechanical properties of this kind of materials should be improved. In this work, chitosan/hydroxyapatite composite rods with multilayer structure were reinforced using a bio-crosslinker to improve their mechanical properties and anti-degradation ability. The SEM results revealed that the composite rods had a tree-ring structure. The bending strength and bending modulus of the crosslinked rods could arrive at 161 MPa and 7.2 GPa, respectively, increased by 59.4% and 26.3% compared with uncrosslinked ones (p<0.05). The enzymatic degradation studies indicated that genipin crosslinking could effectively enhance the biostability of the composite rods. Consequently, genipin-crosslinked chitosan/hydroxyapatite composite rods with excellent mechanical properties would be a novel device used for internal fixation of bone fracture." @default.
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- W2037081359 date "2013-03-01" @default.
- W2037081359 modified "2023-09-25" @default.
- W2037081359 title "In situ forming chitosan/hydroxyapatite rods reinforced via genipin crosslinking" @default.
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- W2037081359 doi "https://doi.org/10.1016/j.matlet.2012.12.009" @default.
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