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- W2042889596 abstract "Ethyl methanesulfonate (EMS) induced high frequencies of dominant lethal mutations in mouse epididymal spermatozoa and late spermatids and lower frequencies in vas deferens spermatozoa and early spermatids. Pre-meiotic germ cell stages were relatively resistent to the induction of dominant lethals and cell killing. The same dose of the chemical also induced high frequencies of translocations among the F1 offspring, the frequencies being highest among offspring from the germ cell stages most sensitive to the induction of dominant lethals. Evidence is presented which support the concept that F1 male sterility, like F1 male semi-sterility, has a basis of chromosome breakage." @default.
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- W2042889596 date "1968-09-01" @default.
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- W2042889596 title "Ethyl methanesulfonate-induced chromosome breakage in the mouse" @default.
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- W2042889596 doi "https://doi.org/10.1016/0027-5107(68)90045-6" @default.
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