FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044425664> ?p ?o ?g. }

• W2044425664 endingPage "376" @default.
• W2044425664 startingPage "369" @default.
• W2044425664 abstract "The vast majority of T cells present in chronic inflammatory lesions are of the helper-inducer/memory (CD45RO+CD29+) phenotype; suppressor-inducer/naive cells (CD45RA+) are virtually absent. Furthermore, CD4+ T cells are found more frequently than CD8+ cells. Previous in vitro studies have suggested that this may be, in part, due to the increased capacity of CD45RO+CD29+ T cells to bind to endothelium and, thus, enter inflammatory foci but no in vivo evidence for preferential migration exists. To investigate this, suction blisters were generated over a purified protein derivative of tuberculin-induced delayed-type hypersensitivity lesions in humans and the phenotype of the blister cells was studied. At all time points, a preponderance of CD45RO+CD29+ cells over CD45RA+ cells and of CD4 over CD8 cells was demonstrated. Because of the rapid kinetics, this appears to represent preferential migration of these cell types rather than in situ proliferation or phenotype conversion. In addition the expression of the CD45RO but not the CD45RA antigen was up-regulated on blister T cells compared to blood T cells. Analysis of blister fluid showed high concentrations of interleukin 6 but not tumor necrosis factor-α or lymphotoxin. This study shows for the first time directly in vivo that CD45RO+ T cells migrate preferentially into inflammatory lesions. Furthermore, it illustrates the potential usefulness of this system in the analysis of the early phases of the immune inflammatory response." @default.
• W2044425664 created "2016-06-24" @default.
• W2044425664 creator A5017107411 @default.
• W2044425664 creator A5020229499 @default.
• W2044425664 creator A5028150556 @default.
• W2044425664 creator A5039215491 @default.
• W2044425664 creator A5043653963 @default.
• W2044425664 creator A5057803401 @default.
• W2044425664 date "1991-02-01" @default.
• W2044425664 modified "2023-10-16" @default.
• W2044425664 title "Selective migration of the human helper-inducer memory T cell subset: confirmation byin vivo cellular kinetic studies" @default.
• W2044425664 cites W1481636931 @default.
• W2044425664 cites W1495149107 @default.
• W2044425664 cites W1559971535 @default.
• W2044425664 cites W1568059997 @default.
• W2044425664 cites W1570191167 @default.
• W2044425664 cites W1589875948 @default.
• W2044425664 cites W1622869407 @default.
• W2044425664 cites W1818805711 @default.
• W2044425664 cites W1877478601 @default.
• W2044425664 cites W1963569673 @default.
• W2044425664 cites W1964132702 @default.
• W2044425664 cites W1977922751 @default.
• W2044425664 cites W1986692826 @default.
• W2044425664 cites W2016099749 @default.
• W2044425664 cites W2027472039 @default.
• W2044425664 cites W2031086429 @default.
• W2044425664 cites W2035126938 @default.
• W2044425664 cites W2036897088 @default.
• W2044425664 cites W2054370905 @default.
• W2044425664 cites W2057784785 @default.
• W2044425664 cites W2067004325 @default.
• W2044425664 cites W2075456216 @default.
• W2044425664 cites W2079457579 @default.
• W2044425664 cites W2082866606 @default.
• W2044425664 cites W2085644886 @default.
• W2044425664 cites W2086487142 @default.
• W2044425664 cites W2119695877 @default.
• W2044425664 cites W2125109040 @default.
• W2044425664 cites W2140202337 @default.
• W2044425664 cites W2156847997 @default.
• W2044425664 cites W2168878865 @default.
• W2044425664 cites W2341969299 @default.
• W2044425664 doi "https://doi.org/10.1002/eji.1830210218" @default.
• W2044425664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1671837" @default.
• W2044425664 hasPublicationYear "1991" @default.
• W2044425664 type Work @default.
• W2044425664 sameAs 2044425664 @default.
• W2044425664 citedByCount "97" @default.
• W2044425664 countsByYear W20444256642013 @default.
• W2044425664 countsByYear W20444256642014 @default.
• W2044425664 countsByYear W20444256642018 @default.
• W2044425664 crossrefType "journal-article" @default.
• W2044425664 hasAuthorship W2044425664A5017107411 @default.
• W2044425664 hasAuthorship W2044425664A5020229499 @default.
• W2044425664 hasAuthorship W2044425664A5028150556 @default.
• W2044425664 hasAuthorship W2044425664A5039215491 @default.
• W2044425664 hasAuthorship W2044425664A5043653963 @default.
• W2044425664 hasAuthorship W2044425664A5057803401 @default.
• W2044425664 hasConcept C129374314 @default.
• W2044425664 hasConcept C147483822 @default.
• W2044425664 hasConcept C149532602 @default.
• W2044425664 hasConcept C150903083 @default.
• W2044425664 hasConcept C154317977 @default.
• W2044425664 hasConcept C167672396 @default.
• W2044425664 hasConcept C17991360 @default.
• W2044425664 hasConcept C202751555 @default.
• W2044425664 hasConcept C203014093 @default.
• W2044425664 hasConcept C207001950 @default.
• W2044425664 hasConcept C2776090121 @default.
• W2044425664 hasConcept C55493867 @default.
• W2044425664 hasConcept C67662055 @default.
• W2044425664 hasConcept C86803240 @default.
• W2044425664 hasConcept C8891405 @default.
• W2044425664 hasConcept C95444343 @default.
• W2044425664 hasConceptScore W2044425664C129374314 @default.
• W2044425664 hasConceptScore W2044425664C147483822 @default.
• W2044425664 hasConceptScore W2044425664C149532602 @default.
• W2044425664 hasConceptScore W2044425664C150903083 @default.
• W2044425664 hasConceptScore W2044425664C154317977 @default.
• W2044425664 hasConceptScore W2044425664C167672396 @default.
• W2044425664 hasConceptScore W2044425664C17991360 @default.
• W2044425664 hasConceptScore W2044425664C202751555 @default.
• W2044425664 hasConceptScore W2044425664C203014093 @default.
• W2044425664 hasConceptScore W2044425664C207001950 @default.
• W2044425664 hasConceptScore W2044425664C2776090121 @default.
• W2044425664 hasConceptScore W2044425664C55493867 @default.
• W2044425664 hasConceptScore W2044425664C67662055 @default.
• W2044425664 hasConceptScore W2044425664C86803240 @default.
• W2044425664 hasConceptScore W2044425664C8891405 @default.
• W2044425664 hasConceptScore W2044425664C95444343 @default.
• W2044425664 hasIssue "2" @default.
• W2044425664 hasLocation W20444256641 @default.
• W2044425664 hasLocation W20444256642 @default.
• W2044425664 hasOpenAccess W2044425664 @default.
• W2044425664 hasPrimaryLocation W20444256641 @default.
• W2044425664 hasRelatedWork W2002809032 @default.
• W2044425664 hasRelatedWork W2049687639 @default.

• next