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- W2062858052 abstract "This study was aimed to evaluate the 5, 10-methylenetetrahydrofolate reductase (MTHFR) C677T mutation in eastern Uttar Pradesh population.Polymerase chain reaction (PCR) using specific primers followed by amplicon digestion by Hinf I restriction enzyme was used for MTHFR C677T polymorphism analysis. Total 250 subjects were analyzed.The CC genotype was found in 192 subjects, followed by CT in 56 subjects and TT in 2 subject. Genotype frequencies of CC, CT and TT were 0.768, 0.224 and 0.008, respectively. The frequency of C allele was found to be 0.88 and that of T allele was 0.12.It is evident from the results of the present study that the percentage of homozygous genotype (CC) is highest in the target population." @default.
- W2062858052 created "2016-06-24" @default.
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- W2062858052 date "2012-01-01" @default.
- W2062858052 modified "2023-09-27" @default.
- W2062858052 title "Prevalence of methylenetetrahydrofolate reductase C677T polymorphism in eastern Uttar Pradesh" @default.
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- W2062858052 doi "https://doi.org/10.4103/0971-6866.96645" @default.
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