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- W2068530898 abstract "In systemic inflammation and sepsis, the endo-cannabinoid system is upregulated [1]. While it is known that neuronal cannabinoid signalling via cannabinoid receptor-1 (CB1) in the central nervous system represents an intrinsic neuroprotective response [2] and exerts anti-epileptic activity [3], inhibition of CB1 (CB1inh) has been suggested as an experimental target for sepsis therapy [4]. We studied the effects of CB1inh in rats with experimental sepsis during anesthesia induction with pentobarbital." @default.
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- W2068530898 date "2011-02-01" @default.
- W2068530898 modified "2023-10-14" @default.
- W2068530898 title "Cannabinoid receptor-1 inhibition causes anesthetic-induced excitation in septic rats" @default.
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- W2068530898 doi "https://doi.org/10.1186/cc9780" @default.
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