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• W2070174447 abstract "Nutritional status is both important and difficult to assess in patients with Duchenne muscular dystrophy (DMD), particularly in those requiring mechanical ventilation (MV). The current authors evaluated body composition (bio-impedancemetry), resting energy expenditure (REE; indirect calorimetry) and energy intake in 20 adult patients with DMD using home MV (nocturnal: n = 13; continuous: n = 7) and 12 age-matched healthy controls. The patients were smaller in height than the controls and had a lower body weight. Most of the reduction in body mass index was accounted for by a reduction in fat free mass (FFM). REE (kJ) was significantly reduced in the patients (4559±853 kJ·24 h⁻¹<i>versus</i> 7407±1312 kJ·24 h⁻¹), but the difference disappeared after correction for FFM. REE and FFM were correlated in both the controls and patients, but less strongly in the latter, the lower strength of the association being due to the patients using continuous MV (REE and FFM uncorrelated). The food intake of the patients was 1.2±0.4 greater than their REE. This study shows that patients with advanced forms of Duchenne muscular dystrophy have balanced energy intakes and resting energy expenditure." @default.
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• W2070174447 date "2005-04-01" @default.
• W2070174447 modified "2023-10-03" @default.
• W2070174447 title "Resting energy expenditure in Duchenne patients using home mechanical ventilation" @default.
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• W2070174447 doi "https://doi.org/10.1183/09031936.05.00031304" @default.
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