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- W2077830261 abstract "In the current study, we investigated the effects of heat-treated Lactobacillus crispatus KT strains on allergic response in mice. We found that the number of interferon (IFN)-γ+CD4+ cells was higher in C3H/HeN mouse spleen cultures incubated with L. crispatus KT strains than in those cultured with Lactobacillus JCM type cultures. The serum immunoglobulin E levels in NC/Nga mice that were administered KT strains were lower than those in the mice that were not given any bacterium. The ratio of spleen IFN-γ+CD4+/interleukin-4+CD4+ was highest in mice given L. crispatus KT-11. L. crispatus KT-11 also increased the expression of Toll-like receptor (TLR) 2, nucleotide-binding oligomerization domain (NOD) 1, and NOD2 in C3H/HeN mouse Peyer’s patch cells. These results suggest that the L. crispatus KT-11 strain reduces allergic symptoms in NC/Nga mice via the adjustment of the type 1 helper T cell and type 2 helper T cell balance via TLR2, NOD1, and NOD2." @default.
- W2077830261 created "2016-06-24" @default.
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- W2077830261 date "2009-05-26" @default.
- W2077830261 modified "2023-10-16" @default.
- W2077830261 title "Heat-Treated <i>Lactobacillus crispatus</i> KT Strains Reduce Allergic Symptoms in Mice" @default.
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- W2077830261 doi "https://doi.org/10.1021/jf900703q" @default.
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