Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078394463> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2078394463 endingPage "1682" @default.
- W2078394463 startingPage "1675" @default.
- W2078394463 abstract "Differentiation between viable myocardium and scar tissue in segments with abnormal contraction has important consequences in the clinical management of patients with coronary artery disease. Positron emission tomography (PET) can identify viable tissue using 18F-fluorodeoxyglucose (FDG). However, application of PET for daily routine is limited. In this study, FDG uptake was visualized with single photon emission computed tomography (SPECT) and compared with regional perfusion assessed with thallium-201 (201Tl) SPECT. The scintigraphic findings were related to regional wall motion determined with two-dimensional echocardiography. Patients (n = 9) with wall motion abnormalities underwent FDG SPECT and resting 201Tl SPECT. To control the metabolic status patients were studied with a hyperinsulinaemic euglycemic clamp during FDG SPECT. Analysis of reconstructed data was performed visually and semiquantitatively using circumferential profiles. High-quality images were obtained. Eight 201Tl defects showed concordantly decreased FDG uptake (metabolism-perfusion matches) indicating scarred tissue, whereas six regions of hypoperfusion demonstrated a relatively increased FDG uptake (mismatches), suggesting viable myocardium. Semiquantitative analysis confirmed visual findings. Mean 201Tl and FDG activities were not significantly different in matching defects. In mismatches the mean FDG activity was 81 +/- 11% vs 64 +/- 9% mean 201Tl activity (P < 0.0001). In four of six segments with increased FDG uptake, two-dimensional echo revealed hypokinesia. Seven of eight regions with a matching defect in contrast were akinetic. Thus, in the areas with a mismatch contractility was preserved. We conclude that FDG uptake can be visualized with SPECT. Furthermore, our preliminary observations suggest that this approach can identify viable tissue." @default.
- W2078394463 created "2016-06-24" @default.
- W2078394463 creator A5016972795 @default.
- W2078394463 creator A5018481009 @default.
- W2078394463 creator A5033479894 @default.
- W2078394463 creator A5053372006 @default.
- W2078394463 creator A5055872647 @default.
- W2078394463 creator A5057617603 @default.
- W2078394463 creator A5072070146 @default.
- W2078394463 creator A5086724216 @default.
- W2078394463 creator A5087389457 @default.
- W2078394463 date "1993-12-02" @default.
- W2078394463 modified "2023-09-23" @default.
- W2078394463 title "Feasibility of assessing regional myocardial uptake of 18F-fluorodeoxyglucose using single photon emission computed tomography" @default.
- W2078394463 doi "https://doi.org/10.1093/eurheartj/14.12.1675" @default.
- W2078394463 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8131767" @default.
- W2078394463 hasPublicationYear "1993" @default.
- W2078394463 type Work @default.
- W2078394463 sameAs 2078394463 @default.
- W2078394463 citedByCount "51" @default.
- W2078394463 crossrefType "journal-article" @default.
- W2078394463 hasAuthorship W2078394463A5016972795 @default.
- W2078394463 hasAuthorship W2078394463A5018481009 @default.
- W2078394463 hasAuthorship W2078394463A5033479894 @default.
- W2078394463 hasAuthorship W2078394463A5053372006 @default.
- W2078394463 hasAuthorship W2078394463A5055872647 @default.
- W2078394463 hasAuthorship W2078394463A5057617603 @default.
- W2078394463 hasAuthorship W2078394463A5072070146 @default.
- W2078394463 hasAuthorship W2078394463A5086724216 @default.
- W2078394463 hasAuthorship W2078394463A5087389457 @default.
- W2078394463 hasConcept C126838900 @default.
- W2078394463 hasConcept C146957229 @default.
- W2078394463 hasConcept C164705383 @default.
- W2078394463 hasConcept C179104552 @default.
- W2078394463 hasConcept C185592680 @default.
- W2078394463 hasConcept C2775842073 @default.
- W2078394463 hasConcept C2775880387 @default.
- W2078394463 hasConcept C2777415128 @default.
- W2078394463 hasConcept C2778064278 @default.
- W2078394463 hasConcept C2778213512 @default.
- W2078394463 hasConcept C2780441642 @default.
- W2078394463 hasConcept C2989005 @default.
- W2078394463 hasConcept C39133596 @default.
- W2078394463 hasConcept C559099789 @default.
- W2078394463 hasConcept C71924100 @default.
- W2078394463 hasConceptScore W2078394463C126838900 @default.
- W2078394463 hasConceptScore W2078394463C146957229 @default.
- W2078394463 hasConceptScore W2078394463C164705383 @default.
- W2078394463 hasConceptScore W2078394463C179104552 @default.
- W2078394463 hasConceptScore W2078394463C185592680 @default.
- W2078394463 hasConceptScore W2078394463C2775842073 @default.
- W2078394463 hasConceptScore W2078394463C2775880387 @default.
- W2078394463 hasConceptScore W2078394463C2777415128 @default.
- W2078394463 hasConceptScore W2078394463C2778064278 @default.
- W2078394463 hasConceptScore W2078394463C2778213512 @default.
- W2078394463 hasConceptScore W2078394463C2780441642 @default.
- W2078394463 hasConceptScore W2078394463C2989005 @default.
- W2078394463 hasConceptScore W2078394463C39133596 @default.
- W2078394463 hasConceptScore W2078394463C559099789 @default.
- W2078394463 hasConceptScore W2078394463C71924100 @default.
- W2078394463 hasIssue "12" @default.
- W2078394463 hasLocation W20783944631 @default.
- W2078394463 hasLocation W20783944632 @default.
- W2078394463 hasOpenAccess W2078394463 @default.
- W2078394463 hasPrimaryLocation W20783944631 @default.
- W2078394463 hasRelatedWork W2000628798 @default.
- W2078394463 hasRelatedWork W2012576700 @default.
- W2078394463 hasRelatedWork W2048870758 @default.
- W2078394463 hasRelatedWork W2059807863 @default.
- W2078394463 hasRelatedWork W2078394463 @default.
- W2078394463 hasRelatedWork W2093952605 @default.
- W2078394463 hasRelatedWork W2170524884 @default.
- W2078394463 hasRelatedWork W2242030499 @default.
- W2078394463 hasRelatedWork W2417317414 @default.
- W2078394463 hasRelatedWork W2978915138 @default.
- W2078394463 hasVolume "14" @default.
- W2078394463 isParatext "false" @default.
- W2078394463 isRetracted "false" @default.
- W2078394463 magId "2078394463" @default.
- W2078394463 workType "article" @default.