FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082487229> ?p ?o ?g. }

• W2082487229 endingPage "S24" @default.
• W2082487229 startingPage "S19" @default.
• W2082487229 abstract "Diabetic foot disease is an important complication of diabetes. The development and outcome of foot ulcers are related to the interplay between numerous diabetes-related factors such as nerve dysfunction, impaired wound healing and microvascular and/or macrovascular disease. The formation of advanced glycation end products (AGEs) has been recognized as an important pathophysiological mechanism in the development of diabetic complications. Several mechanisms have been proposed by which AGEs lead to diabetic complications such as the accumulation of AGEs in the extracellular matrix causing aberrant cross-linking, the binding of circulating AGEs to the receptor of AGEs (RAGE) on different cell types and activation of key cell signalling pathways with subsequent modulation of gene expression, and intracellular AGE formation leading to quenching of nitric oxide and impaired function of growth factors. In the last decade, many experimental studies have shown that these effects of AGE formation may play a role in the pathogenesis of micro- and macrovascular complications of diabetes, diabetic neuropathy and impaired wound healing. In recent years also, several clinical studies have shown that glycation is an important pathway in the pathophysiology of those complications that predispose to the development of foot ulcers. Currently, there are a number of ways to prevent or decrease glycation and glycation-induced tissue damage. Although not in the area of neuropathy or wound healing, recent clinical studies have shown that the AGE-breakers may be able to decrease adverse vascular effects of glycation with few side effects. Copyright © 2008 John Wiley & Sons, Ltd." @default.
• W2082487229 created "2016-06-24" @default.
• W2082487229 creator A5010886974 @default.
• W2082487229 creator A5012543616 @default.
• W2082487229 creator A5031265369 @default.
• W2082487229 date "2008-01-01" @default.
• W2082487229 modified "2023-09-30" @default.
• W2082487229 title "Advanced glycation end products and diabetic foot disease" @default.
• W2082487229 cites W1562556996 @default.
• W2082487229 cites W1902029503 @default.
• W2082487229 cites W1965497701 @default.
• W2082487229 cites W1966234811 @default.
• W2082487229 cites W1967959058 @default.
• W2082487229 cites W1971209988 @default.
• W2082487229 cites W1977893502 @default.
• W2082487229 cites W1987796811 @default.
• W2082487229 cites W1990675333 @default.
• W2082487229 cites W1991974656 @default.
• W2082487229 cites W1999684267 @default.
• W2082487229 cites W2000782226 @default.
• W2082487229 cites W2003813921 @default.
• W2082487229 cites W2008586394 @default.
• W2082487229 cites W2012124401 @default.
• W2082487229 cites W2013730613 @default.
• W2082487229 cites W2016321657 @default.
• W2082487229 cites W2018620079 @default.
• W2082487229 cites W2019226618 @default.
• W2082487229 cites W2026473612 @default.
• W2082487229 cites W2032988386 @default.
• W2082487229 cites W2034138847 @default.
• W2082487229 cites W2036050809 @default.
• W2082487229 cites W2042137562 @default.
• W2082487229 cites W2043894007 @default.
• W2082487229 cites W2047964022 @default.
• W2082487229 cites W2049262834 @default.
• W2082487229 cites W2049374654 @default.
• W2082487229 cites W2061892874 @default.
• W2082487229 cites W2064901107 @default.
• W2082487229 cites W2066512884 @default.
• W2082487229 cites W2069588809 @default.
• W2082487229 cites W2071365066 @default.
• W2082487229 cites W2072076332 @default.
• W2082487229 cites W2075422811 @default.
• W2082487229 cites W2081814934 @default.
• W2082487229 cites W2085553949 @default.
• W2082487229 cites W2086321305 @default.
• W2082487229 cites W2096678432 @default.
• W2082487229 cites W2098933502 @default.
• W2082487229 cites W2100407718 @default.
• W2082487229 cites W2109334664 @default.
• W2082487229 cites W2112841292 @default.
• W2082487229 cites W2122567972 @default.
• W2082487229 cites W2130961250 @default.
• W2082487229 cites W2131226296 @default.
• W2082487229 cites W2132176130 @default.
• W2082487229 cites W2133058543 @default.
• W2082487229 cites W2148715056 @default.
• W2082487229 cites W2151763813 @default.
• W2082487229 cites W2153391104 @default.
• W2082487229 cites W2153488117 @default.
• W2082487229 cites W2154729668 @default.
• W2082487229 cites W2156592815 @default.
• W2082487229 cites W2159602704 @default.
• W2082487229 cites W2160234008 @default.
• W2082487229 cites W2162666481 @default.
• W2082487229 cites W2252766049 @default.
• W2082487229 cites W2315801165 @default.
• W2082487229 cites W2337454357 @default.
• W2082487229 cites W2471605942 @default.
• W2082487229 cites W2769264260 @default.
• W2082487229 cites W2283520088 @default.
• W2082487229 doi "https://doi.org/10.1002/dmrr.861" @default.
• W2082487229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18442180" @default.
• W2082487229 hasPublicationYear "2008" @default.
• W2082487229 type Work @default.
• W2082487229 sameAs 2082487229 @default.
• W2082487229 citedByCount "146" @default.
• W2082487229 countsByYear W20824872292012 @default.
• W2082487229 countsByYear W20824872292013 @default.
• W2082487229 countsByYear W20824872292014 @default.
• W2082487229 countsByYear W20824872292015 @default.
• W2082487229 countsByYear W20824872292016 @default.
• W2082487229 countsByYear W20824872292017 @default.
• W2082487229 countsByYear W20824872292018 @default.
• W2082487229 countsByYear W20824872292019 @default.
• W2082487229 countsByYear W20824872292020 @default.
• W2082487229 countsByYear W20824872292021 @default.
• W2082487229 countsByYear W20824872292022 @default.
• W2082487229 countsByYear W20824872292023 @default.
• W2082487229 crossrefType "journal-article" @default.
• W2082487229 hasAuthorship W2082487229A5010886974 @default.
• W2082487229 hasAuthorship W2082487229A5012543616 @default.
• W2082487229 hasAuthorship W2082487229A5031265369 @default.
• W2082487229 hasConcept C10162356 @default.
• W2082487229 hasConcept C126322002 @default.
• W2082487229 hasConcept C134018914 @default.
• W2082487229 hasConcept C141071460 @default.
• W2082487229 hasConcept C147990577 @default.

• next