Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090423920> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2090423920 endingPage "234" @default.
- W2090423920 startingPage "225" @default.
- W2090423920 abstract "Numerous reports indicate that the oxidation of low-density lipoprotein (LDL) can significantly change its metabolic and physiological properties. Most methods for evaluation of LDL oxidation require isolation of lipoprotein, making the procedure laborious and increasing the probability of artifactual modification of LDL. In this paper we describe an immunochemical approach which can be used to measure the oxidation of isolated LDL and apoprotein B in unfractionated serum and to evaluate the effects of antioxidants on these processes. The procedure is based on differential recognition by monoclonal antibodies of native and oxidized lipoproteins. The results obtained with our assay indicate a strong correlation between the changes of apo B epitope expression during oxidation and the formation of conjugated dienes, changes in lipoprotein electrophoretic mobility, and interaction with fibroblast and macrophage receptors. The sensitivity of apo B to oxidation varies greatly among serum samples obtained from individual donors. These differences do not correlate with the differences in sensitivity to oxidation of LDL isolated from the blood samples of the same donors. It is also shown that apo B oxidation in serum can be progressively inhibited in the presence of increasing amounts of various antioxidants." @default.
- W2090423920 created "2016-06-24" @default.
- W2090423920 creator A5036133058 @default.
- W2090423920 creator A5081410653 @default.
- W2090423920 creator A5082640243 @default.
- W2090423920 creator A5088034176 @default.
- W2090423920 date "1995-05-01" @default.
- W2090423920 modified "2023-09-25" @default.
- W2090423920 title "Monoclonal Antibody-Based Immunoassay for Evaluation of Lipoprotein Oxidation" @default.
- W2090423920 doi "https://doi.org/10.1006/abio.1995.1274" @default.
- W2090423920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7545355" @default.
- W2090423920 hasPublicationYear "1995" @default.
- W2090423920 type Work @default.
- W2090423920 sameAs 2090423920 @default.
- W2090423920 citedByCount "9" @default.
- W2090423920 crossrefType "journal-article" @default.
- W2090423920 hasAuthorship W2090423920A5036133058 @default.
- W2090423920 hasAuthorship W2090423920A5081410653 @default.
- W2090423920 hasAuthorship W2090423920A5082640243 @default.
- W2090423920 hasAuthorship W2090423920A5088034176 @default.
- W2090423920 hasBestOaLocation W20904239201 @default.
- W2090423920 hasConcept C159654299 @default.
- W2090423920 hasConcept C185592680 @default.
- W2090423920 hasConcept C195616568 @default.
- W2090423920 hasConcept C203014093 @default.
- W2090423920 hasConcept C2776104379 @default.
- W2090423920 hasConcept C2778163477 @default.
- W2090423920 hasConcept C2779620165 @default.
- W2090423920 hasConcept C2780072125 @default.
- W2090423920 hasConcept C2780420688 @default.
- W2090423920 hasConcept C542903549 @default.
- W2090423920 hasConcept C55493867 @default.
- W2090423920 hasConcept C62746215 @default.
- W2090423920 hasConcept C86803240 @default.
- W2090423920 hasConceptScore W2090423920C159654299 @default.
- W2090423920 hasConceptScore W2090423920C185592680 @default.
- W2090423920 hasConceptScore W2090423920C195616568 @default.
- W2090423920 hasConceptScore W2090423920C203014093 @default.
- W2090423920 hasConceptScore W2090423920C2776104379 @default.
- W2090423920 hasConceptScore W2090423920C2778163477 @default.
- W2090423920 hasConceptScore W2090423920C2779620165 @default.
- W2090423920 hasConceptScore W2090423920C2780072125 @default.
- W2090423920 hasConceptScore W2090423920C2780420688 @default.
- W2090423920 hasConceptScore W2090423920C542903549 @default.
- W2090423920 hasConceptScore W2090423920C55493867 @default.
- W2090423920 hasConceptScore W2090423920C62746215 @default.
- W2090423920 hasConceptScore W2090423920C86803240 @default.
- W2090423920 hasIssue "1" @default.
- W2090423920 hasLocation W20904239201 @default.
- W2090423920 hasLocation W20904239202 @default.
- W2090423920 hasOpenAccess W2090423920 @default.
- W2090423920 hasPrimaryLocation W20904239201 @default.
- W2090423920 hasRelatedWork W1485330614 @default.
- W2090423920 hasRelatedWork W1998990144 @default.
- W2090423920 hasRelatedWork W2047324684 @default.
- W2090423920 hasRelatedWork W2061889790 @default.
- W2090423920 hasRelatedWork W2080320356 @default.
- W2090423920 hasRelatedWork W2094149931 @default.
- W2090423920 hasRelatedWork W2167581539 @default.
- W2090423920 hasRelatedWork W2168149590 @default.
- W2090423920 hasRelatedWork W2438116370 @default.
- W2090423920 hasRelatedWork W4281611676 @default.
- W2090423920 hasVolume "227" @default.
- W2090423920 isParatext "false" @default.
- W2090423920 isRetracted "false" @default.
- W2090423920 magId "2090423920" @default.
- W2090423920 workType "article" @default.