FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096570372> ?p ?o ?g. }

• W2096570372 endingPage "185" @default.
• W2096570372 startingPage "176" @default.
• W2096570372 abstract "The melting of DNA in the presence of osmolytes has been studied with the intention of obtaining information about how base pair stability is affected by changes in solution conditions. In previous investigations, the melting enthalpies were assumed to be constant as osmolalities change, but no systematic evaluation of whether this condition is true has been offered. This paper presents calorimetric data on the melting of two synthetic DNA samples in the presence of a number of common osmolytes. Poly(dAdT)·poly(dTdA) and poly(dGdC)·poly(dCdG) melting have been examined by differential scanning calorimetry in solutions containing ethylene glycol, glycerol, sucrose, urea, betaine, PEG 200 and PEG 1450 at increasing osmolalities. The results show small, but significant changes in the enthalpy of melting of the two polynucleotides that are different, depending on the structure of the cosolvent. The polyols, ethylene glycol, glycerol, PEG 200 and also urea all show decreases in melting enthalpy, while betaine and sucrose display increases with increasing concentration of cosolvent. The large stabilizing PEG 1450 shows no change within the experimental errors. Using concepts relating to preferential interactions of the cosolvents with the DNA base pairs, it is possible to interpret some of the observed changes in the thermodynamic properties of melting. The results indicate that there is strong entropy–enthalpy compensation upon melting base pairs, but entropy increases dominate to cause the decreases in stability with increased cosolvent concentration. Excess hydration parameters are evaluated and their magnitudes discussed in terms of changes in cosolvent interactions with the DNA base pairs." @default.
• W2096570372 created "2016-06-24" @default.
• W2096570372 creator A5035151394 @default.
• W2096570372 creator A5072406189 @default.
• W2096570372 creator A5073935648 @default.
• W2096570372 date "2007-03-01" @default.
• W2096570372 modified "2023-10-03" @default.
• W2096570372 title "Enthalpies of DNA melting in the presence of osmolytes" @default.
• W2096570372 cites W1487327920 @default.
• W2096570372 cites W1562907760 @default.
• W2096570372 cites W1572204111 @default.
• W2096570372 cites W1964169489 @default.
• W2096570372 cites W1964818283 @default.
• W2096570372 cites W1968054603 @default.
• W2096570372 cites W1970157213 @default.
• W2096570372 cites W1972956664 @default.
• W2096570372 cites W1979134948 @default.
• W2096570372 cites W1982999905 @default.
• W2096570372 cites W1985107466 @default.
• W2096570372 cites W1996260051 @default.
• W2096570372 cites W1998540455 @default.
• W2096570372 cites W2002170773 @default.
• W2096570372 cites W2015019742 @default.
• W2096570372 cites W2021387846 @default.
• W2096570372 cites W2024683933 @default.
• W2096570372 cites W2025607597 @default.
• W2096570372 cites W2041771820 @default.
• W2096570372 cites W2044542007 @default.
• W2096570372 cites W2046615922 @default.
• W2096570372 cites W2047443826 @default.
• W2096570372 cites W2050152524 @default.
• W2096570372 cites W2051452957 @default.
• W2096570372 cites W2060002111 @default.
• W2096570372 cites W2065204524 @default.
• W2096570372 cites W2072682072 @default.
• W2096570372 cites W2077922007 @default.
• W2096570372 cites W2083121396 @default.
• W2096570372 cites W2084744878 @default.
• W2096570372 cites W2085123622 @default.
• W2096570372 cites W2087683394 @default.
• W2096570372 cites W2090656725 @default.
• W2096570372 cites W2124146425 @default.
• W2096570372 cites W2136801450 @default.
• W2096570372 cites W2141525074 @default.
• W2096570372 cites W2165633081 @default.
• W2096570372 doi "https://doi.org/10.1016/j.bpc.2006.07.013" @default.
• W2096570372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16920250" @default.
• W2096570372 hasPublicationYear "2007" @default.
• W2096570372 type Work @default.
• W2096570372 sameAs 2096570372 @default.
• W2096570372 citedByCount "60" @default.
• W2096570372 countsByYear W20965703722012 @default.
• W2096570372 countsByYear W20965703722013 @default.
• W2096570372 countsByYear W20965703722014 @default.
• W2096570372 countsByYear W20965703722015 @default.
• W2096570372 countsByYear W20965703722016 @default.
• W2096570372 countsByYear W20965703722017 @default.
• W2096570372 countsByYear W20965703722018 @default.
• W2096570372 countsByYear W20965703722019 @default.
• W2096570372 countsByYear W20965703722020 @default.
• W2096570372 countsByYear W20965703722021 @default.
• W2096570372 countsByYear W20965703722022 @default.
• W2096570372 countsByYear W20965703722023 @default.
• W2096570372 crossrefType "journal-article" @default.
• W2096570372 hasAuthorship W2096570372A5035151394 @default.
• W2096570372 hasAuthorship W2096570372A5072406189 @default.
• W2096570372 hasAuthorship W2096570372A5073935648 @default.
• W2096570372 hasConcept C121332964 @default.
• W2096570372 hasConcept C127160389 @default.
• W2096570372 hasConcept C129564387 @default.
• W2096570372 hasConcept C13530604 @default.
• W2096570372 hasConcept C178790620 @default.
• W2096570372 hasConcept C185592680 @default.
• W2096570372 hasConcept C2777516009 @default.
• W2096570372 hasConcept C3288061 @default.
• W2096570372 hasConcept C39519442 @default.
• W2096570372 hasConcept C55493867 @default.
• W2096570372 hasConcept C97355855 @default.
• W2096570372 hasConceptScore W2096570372C121332964 @default.
• W2096570372 hasConceptScore W2096570372C127160389 @default.
• W2096570372 hasConceptScore W2096570372C129564387 @default.
• W2096570372 hasConceptScore W2096570372C13530604 @default.
• W2096570372 hasConceptScore W2096570372C178790620 @default.
• W2096570372 hasConceptScore W2096570372C185592680 @default.
• W2096570372 hasConceptScore W2096570372C2777516009 @default.
• W2096570372 hasConceptScore W2096570372C3288061 @default.
• W2096570372 hasConceptScore W2096570372C39519442 @default.
• W2096570372 hasConceptScore W2096570372C55493867 @default.
• W2096570372 hasConceptScore W2096570372C97355855 @default.
• W2096570372 hasIssue "1-3" @default.
• W2096570372 hasLocation W20965703721 @default.
• W2096570372 hasLocation W20965703722 @default.
• W2096570372 hasOpenAccess W2096570372 @default.
• W2096570372 hasPrimaryLocation W20965703721 @default.
• W2096570372 hasRelatedWork W1870326947 @default.
• W2096570372 hasRelatedWork W1988095424 @default.
• W2096570372 hasRelatedWork W2008678667 @default.
• W2096570372 hasRelatedWork W2021908343 @default.

• next